Khan O, Nixon H H
Br J Surg. 1978 Nov;65(11):804-7. doi: 10.1002/bjs.1800651112.
In a controlled trial in children aged 2 days to 16 years undergoing large bowel surgery a group of 15 patients had preoperative mechanical bowel preparation and oral neomycin while a second group of 15 patients was similarly prepared but also had preoperative and postoperative metronidazole medication. Five of the 9 postoperative infections in the first group involved Bacteroides spp. but no anaerobe was found in the 3 wound infections in the metronidazole group.
在一项针对年龄在2天至16岁接受大肠手术儿童的对照试验中,一组15名患者进行了术前机械肠道准备并口服新霉素,而另一组15名患者进行了类似的准备,但术前和术后还接受了甲硝唑治疗。第一组9例术后感染中有5例涉及拟杆菌属,但甲硝唑组的3例伤口感染中未发现厌氧菌。