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采用计算建模和实验验证设计电阻抗谱传感手术钻。

Design of electrical impedance spectroscopy sensing surgical drill using computational modelling and experimental validation.

机构信息

Thayer School of Engineering, Dartmouth College, Hanover, NH 03766, United States of America.

Geisel School of Medicine, Dartmouth College, Hanover, NH 03766, United States of America.

出版信息

Biomed Phys Eng Express. 2022 Dec 19;9(1). doi: 10.1088/2057-1976/ac9f4d.

Abstract

Electrical Impedance Spectroscopy (EIS) sensing surgical instruments could provide valuable and real-time feedback to surgeons about hidden tissue boundaries, therefore reducing the risk of iatrogenic injuries. In this paper, we present an EIS sensing surgical drill as an example instrument and introduce a strategy to optimize the mono-polar electrode geometry using a finite element method (FEM)-based computational model and experimental validation. An empirical contact impedance model and an adaptive mesh refinement protocol were developed to accurately preserve the behaviour of sensing electrodes as they approach high impedance boundaries. Specifically, experiments with drill-bit, cylinder, and conical geometries suggested a 15%-35% increase in resistance as the sensing electrode approached a high impedance boundary. Simulations achieved a maximum mean experiment-to-simulation mismatch of +1.7% for the drill-bit and +/-11% range for other electrode geometries. The simulations preserved the increase in resistance behaviour near the high impedance boundary. This highly accurate simulation framework allows us a mechanism for optimizing sensor geometry without costly experimental evaluation.

摘要

基于有限元方法(FEM)的计算模型和实验验证,本文提出了一种优化单极电极几何形状的策略,以电阻抗谱(EIS)感测手术器械可以为外科医生提供有关隐藏组织边界的有价值和实时反馈,从而降低医源性损伤的风险。本文以 EIS 感测手术钻头为例,介绍了一种策略,使用基于有限元方法(FEM)的计算模型和实验验证来优化单极电极几何形状。我们开发了一个经验接触阻抗模型和一个自适应网格细化协议,以准确地保留感测电极接近高阻抗边界时的行为。具体来说,钻头、圆柱和圆锥形几何形状的实验表明,当感测电极接近高阻抗边界时,电阻会增加 15%-35%。模拟钻头的最大平均实验-模拟差值为+1.7%,而其他电极几何形状的差值范围为+/-11%。模拟保留了高阻抗边界附近电阻增加的行为。这个高度精确的模拟框架为我们提供了一种优化传感器几何形状的机制,而无需进行昂贵的实验评估。

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