John Kevin, Lal Amos, Sharma Nitish, ElMeligy Amr, Mishra Ajay K
Department of Critical Care, Believers Church Medical College Hospital, Thiruvalla 689103, Kerala, India.
Division of Pulmonary & Critical Care Medicine, Mayo Clinic, Rochester, MN 55905, United States.
World J Crit Care Med. 2022 May 9;11(3):129-138. doi: 10.5492/wjccm.v11.i3.129.
Among the cardiac complications of coronavirus disease 2019 (COVID-19), one increasingly reported in the literature is myocardial infarction with non-obstructive coronaries (MINOCA). We reviewed all reported cases of MINOCA in COVID-19 patients to summarize its clinical features, evaluation, and treatment. We performed a literature search in Pubmed using the search terms 'COVID-19' and 'MINOCA' or 'non-obstructive coronaries'. Among the reported cases, the mean age was 61.5 years (SD ± 13.4), and 50% were men. Chest pain was the presenting symptom in five patients (62.5%), and hypertension was the most common comorbidity (62.5%). ST-elevation was seen in most patients (87.5%), and the overall mortality rate was 37.5%. MINOCA in COVID-19 is an entity with a broad differential diagnosis. Therefore, a uniform algorithm is needed in its evaluation to ensure timely diagnosis and management.
在2019冠状病毒病（COVID-19）的心脏并发症中，文献中越来越多地报道的一种是无阻塞性冠状动脉心肌梗死（MINOCA）。我们回顾了所有报道的COVID-19患者MINOCA病例，以总结其临床特征、评估和治疗方法。我们在PubMed上使用搜索词“COVID-19”和“MINOCA”或“无阻塞性冠状动脉”进行了文献检索。在报道的病例中，平均年龄为61.5岁（标准差±13.4），50%为男性。五名患者（62.5%）以胸痛为首发症状，高血压是最常见的合并症（62.5%）。大多数患者（87.5%）出现ST段抬高，总死亡率为37.5%。COVID-19中的MINOCA是一种鉴别诊断广泛的疾病。因此，在其评估中需要一种统一的算法，以确保及时诊断和管理。
