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大流行后的谜团：SARS-CoV-2 急性后期后遗症对心血管的影响。

A Post-Pandemic Enigma: The Cardiovascular Impact of Post-Acute Sequelae of SARS-CoV-2.

机构信息

Heart, Vascular, and Thoracic Institute, Cleveland Clinic, Cleveland, OH (TKS, MC, SJC).

Cleveland Clinic Lerner College of Medicine, OH (T.K.S., K.M., K.B.H., K.E., S.J.C., M.K.C.).

出版信息

Circ Res. 2023 May 12;132(10):1358-1373. doi: 10.1161/CIRCRESAHA.122.322228. Epub 2023 May 11.

DOI:10.1161/CIRCRESAHA.122.322228
PMID:37167358
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10171306/
Abstract

COVID-19 has become the first modern-day pandemic of historic proportion, affecting >600 million individuals worldwide and causing >6.5 million deaths. While acute infection has had devastating consequences, postacute sequelae of SARS-CoV-2 infection appears to be a pandemic of its own, impacting up to one-third of survivors and often causing symptoms suggestive of cardiovascular phenomena. This review will highlight the suspected pathophysiology of postacute sequelae of SARS-CoV-2, its influence on the cardiovascular system, and potential treatment strategies.

摘要

COVID-19 已成为具有历史意义的首个现代大流行病，影响了全球超过 6 亿人，并导致超过 650 万人死亡。急性感染造成了毁灭性的后果，而 SARS-CoV-2 感染的后期后遗症似乎是一场独立的大流行病，影响了多达三分之一的幸存者，并经常导致提示心血管现象的症状。这篇综述将重点介绍 SARS-CoV-2 感染后期后遗症的可疑病理生理学、它对心血管系统的影响以及潜在的治疗策略。

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