Department of Internal Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Department of Medical Microbiology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Int J Infect Dis. 2022 Dec;125:132-134. doi: 10.1016/j.ijid.2022.10.040. Epub 2022 Nov 1.
Scrub typhus (caused by Orientia tsutsugamushi) is a neglected and underdiagnosed disease due to its non-specific clinical presentation and challenging diagnostics. We document the first study of direct diagnosis of scrub typhus from the blood sample of a patient by full-length 16S ribosomal RNA gene amplicon analysis using Oxford Nanopore sequencing.
恙虫病（由恙虫东方体引起）由于其非特异性临床表现和诊断困难，是一种被忽视和诊断不足的疾病。我们通过 Oxford Nanopore 测序的全长 16S 核糖体 RNA 基因扩增子分析，从患者的血液样本中直接诊断恙虫病，这是首例此类研究。
