Barr J, Danielsson D
Br Med J. 1971 Feb 27;1(5747):482-5. doi: 10.1136/bmj.1.5747.482.
The overall incidence in gonorrhoea of septic gonococcal dermatitis was found to be 1.9% (3% for the females and 0.7% for the males). In 23 patients the common presenting symptoms were arthritis or arthralgia and bouts of fever, but the characteristic skin lesions served as an early clue to the diagnosis, and Neisseria gonorrhoeae was isolated from the genitourinary tract or from the blood. With the use of immunofluorescent techniques gonococci were also found in smears prepared from the skin lesions. An immune response to gonococci was found with the complement fixation technique in 90% of the patients. The response to treatment with penicillin was prompt, with complete relief from joint pains and fever, usually within two to seven days. The skin lesions faded within a few days, but scars could be observed for up to four weeks.
淋菌性脓毒性皮炎在淋病患者中的总体发病率为1.9%(女性为3%,男性为0.7%)。23例患者常见的症状为关节炎或关节痛以及发热,但特征性皮肤损害是早期诊断的线索,且从泌尿生殖道或血液中分离出了淋病奈瑟菌。使用免疫荧光技术还在取自皮肤损害的涂片上发现了淋球菌。采用补体结合技术在90%的患者中发现了对淋球菌的免疫反应。对青霉素治疗反应迅速,通常在2至7天内关节疼痛和发热完全缓解。皮肤损害在数天内消退,但瘢痕可持续观察到四周。