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腘窝皮肤巨大鳞状细胞癌:一例报告。

Giant cutaneous squamous cell carcinoma of the popliteal fossa skin: A case report.

作者信息

Wang Ke, Li Zhen, Chao Sheng-Wu, Wu Xiao-Wei

机构信息

Department of Burn and Plastic Surgery, The Second Affiliated Hospital of Air Force Military Medical University, Xi'an 710032, Shaanxi Province, China.

Department of Liver, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.

出版信息

World J Clin Cases. 2022 Oct 26;10(30):11004-11009. doi: 10.12998/wjcc.v10.i30.11004.

DOI:10.12998/wjcc.v10.i30.11004
PMID:36338233
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9631129/
Abstract

BACKGROUND

Cutaneous squamous cell carcinoma (cSCC) is a common malignant hyperplasia of the skin epithelium. However, cSCC progressing to giant squamous cell carcinoma of the popliteal fossa skin has not been reported. We used full-thickness skin graft from the lower left quadrant of the abdomen to reconstruct the popliteal fossa skin defect in our patient.

CASE SUMMARY

A 64-year-old woman presented with a 3-year history of a progressively enlarged integumentary tumor located on her left popliteal fossa, which was surgically treated. The resultant defect (15 cm × 25 cm) was repaired using full-thickness skin graft from the lower left quadrant of the abdomen.

CONCLUSION

Full-thickness skin graft is a good choice to repair popliteal fossa defect.

摘要

背景

皮肤鳞状细胞癌(cSCC)是一种常见的皮肤上皮恶性增生性疾病。然而,cSCC进展为腘窝皮肤巨大鳞状细胞癌的情况尚未见报道。我们采用取自左下腹部象限的全厚皮片对患者的腘窝皮肤缺损进行修复。

病例摘要

一名64岁女性,因左腘窝处逐渐增大的体表肿物3年前来就诊,接受了手术治疗。术后形成的缺损(15厘米×25厘米)采用取自左下腹部象限的全厚皮片进行修复。

结论

全厚皮片是修复腘窝缺损的良好选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/090f/9631129/8cfe03c9d775/WJCC-10-11004-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/090f/9631129/f359d7f0a859/WJCC-10-11004-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/090f/9631129/74fde0f39bf1/WJCC-10-11004-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/090f/9631129/8cfe03c9d775/WJCC-10-11004-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/090f/9631129/f359d7f0a859/WJCC-10-11004-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/090f/9631129/74fde0f39bf1/WJCC-10-11004-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/090f/9631129/8cfe03c9d775/WJCC-10-11004-g003.jpg

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Severe inflammation in new-borns induces long-term cognitive impairment by activation of IL-1β/KCC2 signaling during early development.新生儿严重炎症通过早期发育过程中 IL-1β/KCC2 信号的激活诱导长期认知障碍。
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