用于癌症治疗中绕过生物屏障的可转化纳米颗粒。
Transformable nanoparticles to bypass biological barriers in cancer treatment.
作者信息
Ramachandran Mythili, Ma Zhao, Lin Kai, De Souza Cristabelle, Li Yuanpei
机构信息
Department of Biochemistry and Molecular Medicine, University of California-Davis USA
Department of Medicinal Chemistry, Key Laboratory of Chemical Biology, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University Jinan Shandong China.
出版信息
Nanoscale Adv. 2022 Sep 14;4(21):4470-4480. doi: 10.1039/d2na00485b. eCollection 2022 Oct 25.
Nanomedicine based drug delivery platforms provide an interesting avenue to explore for the future of cancer treatment. Here we discuss the barriers for drug delivery in cancer therapeutics and how nanomaterials have been designed to bypass these blockades through stimuli responsive transformation in the most recent update. Nanomaterials that address the challenges of each step provide a promising solution for new cancer therapeutics.
基于纳米医学的药物递送平台为癌症治疗的未来探索提供了一条有趣的途径。在此，我们讨论癌症治疗中药物递送的障碍，以及在最新进展中纳米材料是如何通过刺激响应转变来设计以绕过这些障碍的。应对每个步骤挑战的纳米材料为新型癌症治疗提供了一个有前景的解决方案。
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