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如何应对肝细胞癌:国际肝癌协会给卫生当局的建议

What to do about hepatocellular carcinoma: Recommendations for health authorities from the International Liver Cancer Association.

作者信息

Allaire Manon, Bruix Jordi, Korenjak Marko, Manes Sarah, Maravic Zorana, Reeves Helen, Salem Riad, Sangro Bruno, Sherman Morris

机构信息

AP-HP Sorbonne Université, Hôpital Universitaire Pitié-Salpêtrière, Service d'Hépato-gastroentérologie, Paris, France.

University Hospital Clinic IDIBAPS, Barcelona, Spain.

出版信息

JHEP Rep. 2022 Sep 8;4(12):100578. doi: 10.1016/j.jhepr.2022.100578. eCollection 2022 Dec.

DOI:10.1016/j.jhepr.2022.100578
PMID:36352896
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9638834/
Abstract

Hepatocellular carcinoma (HCC) is a major public health problem worldwide for which the incidence and mortality are similar, pointing to the lack of effective treatment options. Knowing the different issues involved in the management of HCC, from risk factors to screening and management, is essential to improve the prognosis and quality of life of affected individuals. This document summarises the current state of knowledge and the unmet needs for all the different stakeholders in the care of liver cancer, meaning patients, relatives, physicians, regulatory agencies and health authorities so that optimal care can be delivered to patients. The document was commissioned by the International Liver Cancer Association and was reviewed by senior members, including two ex-presidents of the Association. This document lays out the recommended approaches to the societal management of HCC based on the economic status of a given region.

摘要

肝细胞癌(HCC)是一个全球性的重大公共卫生问题,其发病率和死亡率相近,这表明缺乏有效的治疗选择。了解HCC管理中涉及的不同问题,从风险因素到筛查和管理,对于改善受影响个体的预后和生活质量至关重要。本文总结了肝癌护理中所有不同利益相关者(即患者、亲属、医生、监管机构和卫生当局)的当前知识状态和未满足的需求,以便能够为患者提供最佳护理。该文件由国际肝癌协会委托编写,并由包括协会两位前主席在内的资深成员进行了审阅。本文根据特定地区的经济状况,列出了HCC社会管理的推荐方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f4b/9638834/32afce81420e/gr2.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f4b/9638834/f85e086632a6/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f4b/9638834/32afce81420e/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f4b/9638834/b2a4aae3c7fc/fx1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f4b/9638834/8c59cfa80f67/fx2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f4b/9638834/f85e086632a6/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f4b/9638834/32afce81420e/gr2.jpg

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NEJM Evid. 2022 Aug;1(8):EVIDoa2100070. doi: 10.1056/EVIDoa2100070. Epub 2022 Jun 6.
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Changing epidemiology of hepatocellular cancer in the United States: Winning the battle but it is not over yet.美国肝细胞癌流行病学的变化:虽取得胜利,但尚未结束。
Hepatology. 2022 Sep;76(3):546-548. doi: 10.1002/hep.32512. Epub 2022 Apr 22.
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AGA Clinical Practice Guideline on Systemic Therapy for Hepatocellular Carcinoma.
治愈之后:在直接作用抗病毒药物时代,丙肝根除后的肝细胞癌风险应对与监测
J Clin Transl Hepatol. 2025 May 28;13(5):418-424. doi: 10.14218/JCTH.2024.00499. Epub 2025 Feb 8.
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Evolving epidemiology of HCC in Spain.西班牙肝癌流行病学的演变
JHEP Rep. 2025 Jan 30;7(5):101336. doi: 10.1016/j.jhepr.2025.101336. eCollection 2025 May.
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Cancers (Basel). 2025 Mar 28;17(7):1133. doi: 10.3390/cancers17071133.
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