Exposure Dynamics Research Section, Health and Environmental Risk Division, National Institute for Environmental Studies, 16-2 Onogawa, Tsukuba, Ibaraki, 305-8506, Japan.
Healthy Environments and Consumer Safety Branch, Health Canada, 269 Laurier Ave W, A/L 4908D, Ottawa, ON, K1A 0K9, Canada.
Int J Hyg Environ Health. 2023 Jan;247:114046. doi: 10.1016/j.ijheh.2022.114046. Epub 2022 Nov 7.
Human biomonitoring (HBM) data measured in specific contexts or populations provide information for comparing population exposures. There are numerous health-based biomonitoring guidance values, but to locate these values, interested parties need to seek them out individually from publications, governmental reports, websites and other sources. Until now, there has been no central, international repository for this information. Thus, a tool is needed to help researchers, public health professionals, risk assessors, and regulatory decision makers to quickly locate relevant values on numerous environmental chemicals. A free, on-line repository for international health-based guidance values to facilitate the interpretation of HBM data is now available. The repository is referred to as the "Human Biomonitoring Health-Based Guidance Value (HB2GV) Dashboard". The Dashboard represents the efforts of the International Human Biomonitoring Working Group (i-HBM), affiliated with the International Society of Exposure Science. The i-HBM's mission is to promote the use of population-level HBM data to inform public health decision-making by developing harmonized resources to facilitate the interpretation of HBM data in a health-based context. This paper describes the methods used to compile the human biomonitoring health-based guidance values, how the values can be accessed and used, and caveats with using the Dashboard for interpreting HBM data. To our knowledge, the HB2GV Dashboard is the first open-access, curated database of HBM guidance values developed for use in interpreting HBM data. This new resource can assist global HBM data users such as risk assessors, risk managers and biomonitoring programs with a readily available compilation of guidance values.
人体生物监测 (HBM) 数据在特定环境或人群中测量,提供了比较人群暴露情况的信息。有许多基于健康的生物监测指导值,但要找到这些值,感兴趣的各方需要单独从出版物、政府报告、网站和其他来源中寻找。到目前为止,还没有一个集中的、国际性的信息库。因此,需要有一种工具来帮助研究人员、公共卫生专业人员、风险评估人员和监管决策者快速找到关于众多环境化学物质的相关值。现在,有一个免费的在线国际健康指导值知识库,用于促进 HBM 数据的解释。该知识库被称为“人体生物监测健康指导值 (HB2GV) 数据仪表盘”。该数据仪表盘是国际人体生物监测工作组 (i-HBM) 的成果,隶属于国际暴露科学学会。i-HBM 的使命是通过开发协调资源,促进在健康背景下解释 HBM 数据,从而利用人群水平的 HBM 数据为公共卫生决策提供信息。本文介绍了编译人体生物监测健康指导值所使用的方法,如何访问和使用这些值,以及使用数据仪表盘解释 HBM 数据时的注意事项。据我们所知,HB2GV 数据仪表盘是第一个用于解释 HBM 数据的开放获取、策划数据库,是为使用 HBM 数据而开发的。这个新资源可以帮助全球 HBM 数据用户,如风险评估人员、风险管理人员和生物监测计划,提供一个现成的指导值汇编。