Luo Sihai, Mancini Andrea, Lian Enkui, Xu Wenqi, Berté Rodrigo, Li Yi
Department of Chemistry, Norwegian University of Science and Technology (NTNU), 7491 Trondheim, Norway.
Chair in Hybrid Nanosystems, Nanoinstitute Munich, Faculty of Physics, Ludwig-Maximilians-Universität München, Königinstrasse 10, 80539 München, Germany.
Nanomaterials (Basel). 2022 Oct 31;12(21):3842. doi: 10.3390/nano12213842.
Applicable surface-enhanced Raman scattering (SERS) active substrates typically require low-cost patterning methodology, high reproducibility, and a high enhancement factor (EF) over a large area. However, the lack of reproducible, reliable fabrication for large area SERS substrates in a low-cost manner remains a challenge. Here, a patterning method based on nanosphere lithography and adhesion lithography is reported that allows massively parallel fabrication of 10-nm annular gap arrays on large areas. The arrays exhibit excellent reproducibility and high SERS performance, with an EF of up to 10. An effective wearable SERS contact lens for glucose detection is further demonstrated. The technique described here extends the range of SERS-active substrates that can be fabricated over large areas, and holds exciting potential for SERS-based chemical and biomedical detection.
适用的表面增强拉曼散射（SERS）活性基底通常需要低成本的图案化方法、高再现性以及大面积上的高增强因子（EF）。然而，以低成本方式对大面积SERS基底进行可再现、可靠的制造仍然是一个挑战。在此，报道了一种基于纳米球光刻和粘附光刻的图案化方法，该方法允许在大面积上大规模并行制造10纳米环形间隙阵列。这些阵列具有出色的再现性和高SERS性能，增强因子高达10。进一步展示了一种用于葡萄糖检测的有效的可穿戴SERS隐形眼镜。这里描述的技术扩展了可以在大面积上制造的SERS活性基底的范围，并为基于SERS的化学和生物医学检测带来了令人兴奋的潜力。
