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两代人间父母和子女饮食行为对超重和肥胖关联性的影响:来自中国亲子三队列的横断面分析结果。

Influence of Parental and Offspring Dietary Behaviors on the Association of Overweight and Obesity between Two Generations: Results from a Cross-Sectional Analysis of Parent-Offspring Trios in China.

机构信息

National Health Commission Key Laboratory of Reproductive Health, Institute of Child and Adolescent Health, School of Public Health, Peking University, Beijing 100191, China.

Key Laboratory of Environmental Factors and Chronic Disease Control, School of Public Health and Management, Ningxia Medical University, No. 1160, Shengli Street, Xingqing District, Yinchuan 750004, China.

出版信息

Nutrients. 2022 Nov 2;14(21):4625. doi: 10.3390/nu14214625.

Abstract

Limited evidence exists on the influence of dietary behaviors on the association of overweight/obesity between parents and offspring. This study aimed to investigate the influence of dietary behaviors on the association of overweight/obesity between two generations, and puts forward strategies for preventing childhood obesity. Data were obtained from a cross-sectional survey conducted in China; a total of 40,197 parent-offspring pairs were included. Overweight/obesity was defined based on the body mass index and waist circumstance; the association of overweight/obesity between two generations was evaluated by multivariate and binary logistic regression and stratified analyses. Compared with the offspring who were free of parental overweight/obesity, the ORs of offspring with both parental overweight/obesity reached 2.66, 1.72 and 4.04 for general, simple abdominal and compound obesity. The offset effect of dietary behaviors was observed on the association between parental obesity and the offspring's general or simple abdominal obesity, with non-significant ORs when parents or/and offspring had healthy dietary behaviors. It was difficult for a healthy diet alone to offset the high heritability and intergenerational transmission of childhood obesity caused by parental obesity. Multifaceted improvement of lifestyle behaviors, and a combination of individual and family engagement, could be targeted measures to control childhood obesity.

摘要

关于饮食行为对父母与子女超重/肥胖相关性的影响,目前相关证据有限。本研究旨在探讨饮食行为对两代人超重/肥胖相关性的影响,并提出预防儿童肥胖的策略。数据来自中国进行的一项横断面调查,共纳入 40197 对父母-子女对。超重/肥胖的定义基于体重指数和腰围情况;采用多变量和二元逻辑回归以及分层分析评估两代人之间超重/肥胖的相关性。与父母均不超重/肥胖的子女相比,父母双方均超重/肥胖的子女发生普通、单纯性腹部和复合型肥胖的 OR 值分别达到 2.66、1.72 和 4.04。饮食行为的偏移效应观察到在父母肥胖与子女普通或单纯性腹部肥胖之间的相关性,当父母或/和子女有健康的饮食行为时,OR 值无统计学意义。单纯的健康饮食很难抵消父母肥胖导致的儿童肥胖的高遗传性和代际传递。改善生活方式行为的多方面措施,以及个人和家庭参与的结合,可以作为控制儿童肥胖的针对性措施。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a372/9658054/058c50fbdde0/nutrients-14-04625-g001.jpg

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