El-Saadony Mohamed T, Yaqoob Muhammad Umar, Hassan Faiz-Ul, Alagawany Mahmoud, Arif Muhammad, Taha Ayman E, Elnesr Shaaban S, El-Tarabily Khaled A, Abd El-Hack Mohamed E
Department of Agricultural Microbiology, Faculty of Agriculture, Zagazig University, Zagazig, 44511, Egypt.
College of Animal Science, Zhejiang University, Hangzhou, 310058, P. R. China.
Anim Health Res Rev. 2022 Dec;23(2):136-146. doi: 10.1017/S1466252321000220. Epub 2022 Nov 14.
Due to the increasing demand for antibiotic-free livestock products from the consumer side and the ban on the use of antibiotic growth promoters, the poultry feed industry is increasingly interested in developing more alternatives to cope with this problem. Organic acids (butyric acid) have many beneficial effects on poultry health, performance, and egg quality when used in their diet, thus they can be considered for the replacement of antibiotics in livestock production systems. Butyric acid is most efficacious against pathogenic bacteria such as spp. and , and stimulates the population of beneficial gut bacteria. It is a primary energy source for colonocytes and augments the differentiation and maturation of the intestinal cells. Collectively, butyric acid should be considered as an alternative to antibiotic growth promoters, because it reduces pathogenic bacteria and their toxins, enhancing gut health thereby increasing nutrient digestibility, thus leading to improved growth performance and immunity among birds. The possible pathways and mechanisms through which butyric acid enhances gut health and production performance are discussed in this review. Detailed information about the use of butyric acid in poultry and its possible benefits under different conditions are also provided, and the impacts of butyric acid on egg quality and osteoporosis are noted.
由于消费者对无抗生素畜产品的需求不断增加，以及抗生素生长促进剂的使用被禁止，家禽饲料行业越来越有兴趣开发更多替代品来应对这一问题。有机酸（丁酸）在家禽日粮中使用时，对家禽健康、生产性能和蛋品质有许多有益影响，因此可考虑在畜牧生产系统中替代抗生素。丁酸对诸如 spp. 和 等病原菌最有效，并能刺激有益肠道细菌的数量。它是结肠细胞的主要能量来源，并促进肠道细胞的分化和成熟。总体而言，丁酸应被视为抗生素生长促进剂的替代品，因为它能减少病原菌及其毒素，增强肠道健康，从而提高养分消化率，进而改善禽类的生长性能和免疫力。本文综述了丁酸增强肠道健康和生产性能的可能途径及机制。还提供了丁酸在家禽中的使用详细信息及其在不同条件下可能带来的益处，并指出了丁酸对蛋品质和骨质疏松症的影响。
