• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

通过进化模拟对蒙特卡罗探测器模型进行自主数字化仪校准。

Autonomous digitizer calibration of a Monte Carlo detector model through evolutionary simulation.

机构信息

School of Chemical Engineering, University of Birmingham, Birmingham, UK.

School of Physics and Astronomy, University of Birmingham, Birmingham, UK.

出版信息

Sci Rep. 2022 Nov 14;12(1):19535. doi: 10.1038/s41598-022-24022-x.

DOI:10.1038/s41598-022-24022-x
PMID:36376375
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9663564/
Abstract

Simulating the response of a radiation detector is a modelling challenge due to the stochastic nature of radiation, often complex geometries, and multi-stage signal processing. While sophisticated tools for Monte Carlo simulation have been developed for radiation transport, emulating signal processing and data loss must be accomplished using a simplified model of the electronics called the digitizer. Due to a large number of free parameters, calibrating a digitizer quickly becomes an optimisation problem. To address this, we propose a novel technique by which evolutionary algorithms calibrate a digitizer autonomously. We demonstrate this by calibrating six free parameters in a digitizer model for the ADAC Forte. The accuracy of solutions is quantified via a cost function measuring the absolute percent difference between simulated and experimental coincidence count rates across a robust characterisation data set, including three detector configurations and a range of source activities. Ultimately, this calibration produces a count rate response with 5.8% mean difference to the experiment, improving from 18.3% difference when manually calibrated. Using evolutionary algorithms for model calibration is a notable advancement because this method is novel, autonomous, fault-tolerant, and achieved through a direct comparison of simulation to reality. The software used in this work has been made freely available through a GitHub repository.

摘要

模拟辐射探测器的响应是一个建模挑战,因为辐射具有随机性,通常具有复杂的几何形状和多阶段的信号处理。虽然已经开发出用于辐射传输的蒙特卡罗模拟的复杂工具,但必须使用称为数字化仪的电子设备的简化模型来模拟信号处理和数据丢失。由于有大量的自由参数,因此校准数字化仪很快就成为一个优化问题。为了解决这个问题,我们提出了一种新的技术,通过进化算法自主校准数字化仪。我们通过校准 ADAC Forte 数字化仪模型中的六个自由参数来证明这一点。通过使用测量模拟和实验符合计数率之间绝对百分比差异的成本函数来量化解决方案的准确性,该函数跨越了一个稳健的特征数据集,包括三种探测器配置和一系列源活动。最终,这种校准产生的计数率响应与实验相比平均差异为 5.8%,而手动校准的差异为 18.3%。使用进化算法进行模型校准是一个显著的进步,因为这种方法是新颖的、自主的、容错的,并且通过模拟与现实的直接比较来实现。这项工作中使用的软件已经通过 GitHub 存储库免费提供。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b29/9663564/595b8d13c4b7/41598_2022_24022_Fig11_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b29/9663564/f8a950b0c513/41598_2022_24022_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b29/9663564/e4a1e3135bcb/41598_2022_24022_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b29/9663564/df2395730399/41598_2022_24022_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b29/9663564/51cd552bfd38/41598_2022_24022_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b29/9663564/625da160dd34/41598_2022_24022_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b29/9663564/a69c709ad6ea/41598_2022_24022_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b29/9663564/f4bf772dd562/41598_2022_24022_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b29/9663564/3118d06ff33a/41598_2022_24022_Fig8_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b29/9663564/e56524fc9dda/41598_2022_24022_Fig9_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b29/9663564/dcbb9ad5a28a/41598_2022_24022_Fig10_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b29/9663564/595b8d13c4b7/41598_2022_24022_Fig11_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b29/9663564/f8a950b0c513/41598_2022_24022_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b29/9663564/e4a1e3135bcb/41598_2022_24022_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b29/9663564/df2395730399/41598_2022_24022_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b29/9663564/51cd552bfd38/41598_2022_24022_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b29/9663564/625da160dd34/41598_2022_24022_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b29/9663564/a69c709ad6ea/41598_2022_24022_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b29/9663564/f4bf772dd562/41598_2022_24022_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b29/9663564/3118d06ff33a/41598_2022_24022_Fig8_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b29/9663564/e56524fc9dda/41598_2022_24022_Fig9_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b29/9663564/dcbb9ad5a28a/41598_2022_24022_Fig10_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b29/9663564/595b8d13c4b7/41598_2022_24022_Fig11_HTML.jpg

相似文献

1
Autonomous digitizer calibration of a Monte Carlo detector model through evolutionary simulation.通过进化模拟对蒙特卡罗探测器模型进行自主数字化仪校准。
Sci Rep. 2022 Nov 14;12(1):19535. doi: 10.1038/s41598-022-24022-x.
2
Monte Carlo method for gamma spectrometry based on GEANT4 toolkit: Efficiency calibration of BE6530 detector.基于GEANT4工具包的蒙特卡罗γ能谱法:BE6530探测器的效率校准
J Environ Radioact. 2018 Sep;189:109-119. doi: 10.1016/j.jenvrad.2018.03.015. Epub 2018 Apr 10.
3
Measurements and Monte Carlo Simulations of 241Am Activities in Three Skull Phantoms: EURADOS-USTUR Collaboration.三种颅骨模型中 241Am 活度的测量和蒙特卡罗模拟:EURADOS-USTUR 合作研究。
Health Phys. 2019 Aug;117(2):193-201. doi: 10.1097/HP.0000000000001080.
4
Monte Carlo modeling provides accurate calibration factors for radionuclide activity meters.蒙特卡罗模拟为放射性核素活度计提供了精确的校准因子。
Appl Radiat Isot. 2014 Dec;94:158-165. doi: 10.1016/j.apradiso.2014.07.021. Epub 2014 Aug 27.
5
A simple methodology for characterization of germanium coaxial detectors by using Monte Carlo simulation and evolutionary algorithms.一种通过蒙特卡罗模拟和进化算法表征锗同轴探测器的简单方法。
J Environ Radioact. 2015 Nov;149:8-18. doi: 10.1016/j.jenvrad.2015.06.017. Epub 2015 Jul 16.
6
Monte Carlo study of a 60Co calibration field of the Dosimetry Laboratory Seibersdorf.塞伯斯多夫剂量测定实验室60Co校准场的蒙特卡罗研究
Radiat Prot Dosimetry. 2007;125(1-4):153-6. doi: 10.1093/rpd/ncm183. Epub 2007 Mar 3.
7
Monte Carlo simulation of a PhosWatch detector using Geant4 for xenon isotope beta-gamma coincidence spectrum profile and detection efficiency calculations.使用Geant4对PhosWatch探测器进行蒙特卡罗模拟,用于氙同位素β-γ符合能谱轮廓和探测效率计算。
Appl Radiat Isot. 2009 Oct;67(10):1957-63. doi: 10.1016/j.apradiso.2009.07.005. Epub 2009 Jul 18.
8
PET digitization chain for Monte Carlo simulation in GATE.正电子发射断层成像(PET)数据化链在 GATE 中的蒙特卡罗模拟
Phys Med Biol. 2024 Aug 2;69(16). doi: 10.1088/1361-6560/ad638c.
9
Simulation of germanium detector calibration using the Monte Carlo method: comparison between point and surface source models.使用蒙特卡罗方法模拟锗探测器校准:点源模型与面源模型的比较
Radiat Prot Dosimetry. 2005;116(1-4 Pt 2):55-8. doi: 10.1093/rpd/nci111.
10
Gamma spectrometry efficiency calibration using Monte Carlo methods to measure radioactivity of 137Cs in food samples.使用蒙特卡罗方法进行伽马能谱效率校准以测量食品样品中¹³⁷Cs的放射性。
Radiat Prot Dosimetry. 2014 Dec;162(3):220-3. doi: 10.1093/rpd/nct279. Epub 2013 Nov 8.

引用本文的文献

1
Dosimetry model for photobiomodulation based on anthropometric and hemodynamic variables in patients with orofacial pain post-Covid-19: Study protocol for randomized clinical trial.基于人口统计学和血液动力学变量的 COVID-19 后口腔颌面部疼痛患者光生物调节剂量学模型:随机临床试验研究方案。
PLoS One. 2024 Oct 15;19(10):e0309073. doi: 10.1371/journal.pone.0309073. eCollection 2024.

本文引用的文献

1
NEMA NU 1-2018 performance characterization and Monte Carlo model validation of the Cubresa Spark SiPM-based preclinical SPECT scanner.基于古巴雷斯(Cubresa)火花硅光电倍增管(SiPM)的临床前单光子发射计算机断层扫描(SPECT)扫描仪的NEMA NU 1-2018性能表征与蒙特卡罗模型验证
EJNMMI Phys. 2023 Jun 1;10(1):35. doi: 10.1186/s40658-023-00555-6.
2
Coffee bean particle motion in a rotating drum measured using Positron Emission Particle Tracking (PEPT).使用正电子发射颗粒跟踪(PEPT)测量旋转滚筒中的咖啡豆颗粒运动。
Food Res Int. 2023 Jan;163:112253. doi: 10.1016/j.foodres.2022.112253. Epub 2022 Nov 29.
3
Monte Carlo evaluation of hypothetical long axial field-of-view PET scanner using GE Discovery MI PET front-end architecture.
使用 GE Discovery MI PET 前端架构对假设的长轴向视野 PET 扫描仪进行蒙特卡罗评估。
Med Phys. 2022 Feb;49(2):1139-1152. doi: 10.1002/mp.15422. Epub 2022 Jan 10.
4
Recent advances in positron emission particle tracking: a comparative review.正电子发射粒子示踪技术的最新进展:比较综述。
Rep Prog Phys. 2022 Jan 7;85(1). doi: 10.1088/1361-6633/ac3c4c.
5
Advanced Monte Carlo simulations of emission tomography imaging systems with GATE.基于 GATE 的发射断层成像系统的高级蒙特卡罗模拟。
Phys Med Biol. 2021 May 14;66(10). doi: 10.1088/1361-6560/abf276.
6
Technical Note: GATE-RTion: a GATE/Geant4 release for clinical applications in scanned ion beam therapy.技术说明:GATE-RTion:用于扫描离子束治疗临床应用的GATE/Geant4版本。
Med Phys. 2020 Aug;47(8):3675-3681. doi: 10.1002/mp.14242. Epub 2020 Jun 13.
7
Monte Carlo simulation of digital photon counting PET.数字光子计数正电子发射断层扫描的蒙特卡罗模拟
EJNMMI Phys. 2020 Apr 25;7(1):23. doi: 10.1186/s40658-020-00288-w.
8
Positron Emission Particle Tracking of Granular Flows.正电子发射颗粒跟踪技术在颗粒流中的应用。
Annu Rev Chem Biomol Eng. 2020 Jun 7;11:367-396. doi: 10.1146/annurev-chembioeng-011620-120633. Epub 2020 Mar 30.
9
Development and validation of a complete GATE model of the Siemens Inveon trimodal imaging platform.开发和验证西门子 Inveon 三模态成像平台的完整 GATE 模型。
Mol Imaging. 2013 Oct;12(7):1-13.
10
GATE: a simulation toolkit for PET and SPECT.GATE:正电子发射断层扫描(PET)和单光子发射计算机断层扫描(SPECT)的模拟工具包。
Phys Med Biol. 2004 Oct 7;49(19):4543-61. doi: 10.1088/0031-9155/49/19/007.