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孕期猴痘感染综述。

A review of monkeypox infection during pregnancy.

作者信息

Farah Stephanie, Nasr Elena, Ramadan Aya, Sayad Edouard, Jallad Karl

机构信息

LAU Medical Center-Rizk Hospital, Gilbert and Rose-Marie Chagoury School of Medicine, Lebanese American University, Beirut, Lebanon.

Department of Obstetrics and Gynecology, Gilbert and Rose-Marie Chagoury School of Medicine, Lebanese American University, Lebanese American University Medical Center LAUMCRH, Beirut, Lebanon.

出版信息

Int J Gynaecol Obstet. 2023 Jun;161(3):738-743. doi: 10.1002/ijgo.14577. Epub 2022 Dec 1.

Abstract

The present study aimed to review monkeypox infection during pregnancy: its epidemiology and etiology, transmission, clinical manifestations and complications, diagnosis, management, antenatal testing and delivery, prevention, awareness, and recommendations. Monkeypox can spread via vertical transmission. The usual clinical symptoms include fever, rash (vesicles, crust), new genital lesions, or sore throat. It is only recommended to use cidofovir in pregnant patients when they are severely infected with monkeypox. All woman who are at high risk of exposure for monkeypox need to be vaccinated with the smallpox vaccine regardless of their pregnancy status. Monitoring includes regular non-stress test monitoring in addition to ultrasound performed at various stages of pregnancy. High index of suspicion, informed physicians, reporting of cases, and support of research are all needed for the management of monkeypox infection during pregnancy.

摘要

本研究旨在综述孕期猴痘感染

其流行病学、病因、传播、临床表现及并发症、诊断、管理、产前检查与分娩、预防、认识及建议。猴痘可通过垂直传播。常见临床症状包括发热、皮疹(水疱、结痂)、新出现的生殖器病变或咽痛。仅在孕妇严重感染猴痘时推荐使用西多福韦。所有有猴痘高暴露风险的女性无论其妊娠状态如何均需接种天花疫苗。监测包括定期进行无应激试验监测以及在孕期不同阶段进行超声检查。对于孕期猴痘感染的管理,需要高度怀疑指数、告知医生、报告病例以及支持研究。

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