Department of Dermatology, University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA.
Pediatr Dermatol. 2023 May-Jun;40(3):507-510. doi: 10.1111/pde.15180. Epub 2022 Nov 15.
Linear morphea and segmental vitiligo are both autoimmune diseases that are observed in the pediatric population, with rare reports of their co-existence. We describe a case of linear morphea and segmental vitiligo with an overlapping distribution in a pediatric patient and review the literature. Including our own case, we summarize 10 cases of co-occurring segmental vitiligo and morphea in pediatric patients; most of these lesions follow a blaschkolinear distribution, and none of the patients had autoimmune thyroid disease. Although uncommon, the coexistence of segmental vitiligo and linear morphea within lines of Blaschko can occur, and this case suggests that linear morphea and segmental vitiligo may be disorders related to genetic mosaicism.
线性硬斑病和节段性白癜风都是在儿科人群中观察到的自身免疫性疾病，两者同时存在的罕见报告。我们描述了一例儿科患者中线性硬斑病和节段性白癜风的重叠分布病例，并复习了文献。包括我们自己的病例在内，我们总结了 10 例儿科患者同时发生的节段性白癜风和硬斑病；这些病变大多呈 Blaschko 线性分布，且无自身免疫性甲状腺疾病。虽然不常见，但节段性白癜风和线性硬斑病可以同时存在于 Blaschko 线内，本病例提示线性硬斑病和节段性白癜风可能是与遗传嵌合体相关的疾病。
