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中国武汉出院 COVID-19 患者焦虑和抑郁的影响因素。

Influencing factors of anxiety and depression of discharged COVID-19 patients in Wuhan, China.

机构信息

School of Population Medicine and Public Health, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.

National Clinical Research Center for Respiratory Diseases, China-Japan Friendship Hospital, Beijing, China.

出版信息

PLoS One. 2022 Nov 16;17(11):e0276608. doi: 10.1371/journal.pone.0276608. eCollection 2022.

Abstract

OBJECTIVES

This study is intended to assess the prevalence of depression and anxiety in individuals who had recovered from COVID-19 and been discharged from hospital (RD hereafter) in Wuhan, China, and to explore the factors associated with these mental disorders.

METHODS

Participants of this study were the RD who were infected at the beginning of the outbreak from 13 communities in Jianghan District of Wuhan City, Hubei Province, China by convenience sampling in mid-2021. The Generalized Anxiety Disorder Questionnaire, the Patient Health Questionnaire, the Short Version of COVID-19 Stigma Scale, the Peace of Mind Scale, the Resilience Style Questionnaire, and the Perceived Social Support Questionnaire were used to collect relevant information of the participants. Descriptive analyses, Pearson correlation analysis, and logistic regression analysis were used to describe and analyze the data and to examine the factors associated with the mental health status of this population.

RESULTS

In total, we recruited 1601 participants from 3059 COVID-19 patients, and 1541 participants completed the questionnaire survey, with a response rate of 96.25%. Finally, 1297 participants met the inclusion and exclusion criteria in this study, of whom 28.8% and 37.9% reported mild to severe levels of anxiety and depression symptoms. Perceived better mental health status during hospitalization, higher frequency of alcohol use per week, peace of mind, higher education level, and resilience were negatively associated with anxiety, while stigma and history of psychological or emotional counseling before infection was positively associated with anxiety. More severe clinical classification of COVID-19 and stigma (AOR = 1.057, P<0.001) were both positively associated with depression, while perceived better mental health status during hospitalization (AOR = 0.564, P<0.001), higher frequency of alcohol use per week (AOR = 0.462, P = 0.004), peace of mind (AOR = 0.857, P<0.001), and social support (AOR = 0.972, P = 0.034) were negatively associated with depression.

CONCLUSIONS

Tailored interventions on reducing stigma, enhancing mindfulness and social support should be taken into account to alleviate anxiety and depression among RD.

摘要

目的

本研究旨在评估中国武汉出院的 COVID-19 康复者(RD)的抑郁和焦虑患病率,并探讨与这些精神障碍相关的因素。

方法

本研究的参与者是 2021 年中期通过便利抽样从湖北省武汉市江汉区 13 个社区感染 COVID-19 的 RD。采用广泛性焦虑症问卷、患者健康问卷、COVID-19 耻辱感量表短版、安心量表、应对风格问卷和感知社会支持问卷收集参与者的相关信息。采用描述性分析、Pearson 相关分析和逻辑回归分析来描述和分析数据,并检查与该人群心理健康状况相关的因素。

结果

共从 3059 例 COVID-19 患者中招募了 1601 名参与者,有 1541 名参与者完成了问卷调查,应答率为 96.25%。最终,1297 名参与者符合本研究的纳入和排除标准,其中 28.8%和 37.9%报告了轻度至重度焦虑和抑郁症状。住院期间感知到更好的心理健康状况、每周饮酒频率更高、安心、更高的教育水平和更强的适应力与焦虑呈负相关,而耻辱感和感染前心理或情绪咨询史与焦虑呈正相关。COVID-19 更严重的临床分类和耻辱感(AOR=1.057,P<0.001)与抑郁呈正相关,而住院期间感知到更好的心理健康状况(AOR=0.564,P<0.001)、每周饮酒频率更高(AOR=0.462,P=0.004)、安心(AOR=0.857,P<0.001)和社会支持(AOR=0.972,P=0.034)与抑郁呈负相关。

结论

应考虑采取减少耻辱感、增强正念和社会支持的针对性干预措施,以减轻 RD 的焦虑和抑郁。

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