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有精神病风险的青少年的语言标记和基本自我障碍。一项定性研究。

Linguistic markers and basic self-disturbances among adolescents at risk of psychosis. A qualitative study.

作者信息

Baklund Lise, Røssberg Jan Ivar, Møller Paul

机构信息

Division of Mental Health and Addiction, Department of Mental Health Research and Development, Vestre Viken, Drammen, Norway.

Vestre Viken HF, FoU-avdelingen, P.O. Box 800, Drammen 3004, Norway.

出版信息

EClinicalMedicine. 2022 Nov 12;55:101733. doi: 10.1016/j.eclinm.2022.101733. eCollection 2023 Jan.

DOI:10.1016/j.eclinm.2022.101733
PMID:36386038
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9661513/
Abstract

BACKGROUND

Language impairments are key features of schizophrenia spectrum disorders, and have also been suggested to signal enhanced psychosis risk. Incoherence, derailment, and monotonous speaking are however closely related to psychosis onset, and thus not very early markers. Recent phenomenologic-psychiatric studies claim that basic self-disturbance (BSD) may represent more useful early markers.

METHODS

We searched for distinctive irregular linguistics of 30 CHR outpatient adolescents, aged 12-18 years. Standard instruments established psychosis risk and BSD. Participants chose three personal and well manifested BSD phenomena. Ninety verbatim statements were analyzed and grouped into higher order clusters of linguistic irregularities.

FINDINGS

We identified five clusters of irregular language features: distinctive words, describing an atmosphere of unreality; irregular use of prepositions, indicating experiential detachment; shifts of personal pronouns, indicating identity confusion; near-literal use of metaphors and conjunctions indicating existential insecurity, and idiosyncratic use of adjectives indicating perceptual transcendence.

INTERPRETATION

The adolescents provided naturalistic descriptions of experiences that were markedly twisted and almost ineffable. This unique irregular "BSD -language" was highly meaningful in its proper context, expressing informative characteristics of first-personal experiential alterations, essential for early detection. The features may additionally represent precursors of psychosis transition, useful for clinical decision-making.

FUNDING

Foundation Dam, Oslo, Norway (Grant Number 2017/FO143368).

摘要

背景

语言障碍是精神分裂症谱系障碍的关键特征,也被认为是精神病风险增加的信号。然而,语无伦次、话题脱轨和说话单调与精神病发作密切相关,因此不是非常早期的标志物。最近的现象学 - 精神病学研究声称,基本自我障碍(BSD)可能代表更有用的早期标志物。

方法

我们对30名年龄在12至18岁的临床高危(CHR)门诊青少年的独特语言不规则现象进行了研究。使用标准工具确定精神病风险和BSD。参与者选择了三种个人的且表现明显的BSD现象。对90条逐字记录的陈述进行了分析,并将其分组为更高阶的语言不规则集群。

研究结果

我们识别出五类语言不规则特征集群:独特的词汇,描述一种不真实的氛围;介词的不规则使用,表明体验性脱离;人称代词的转换,表明身份混淆;隐喻和连词的近乎字面的使用,表明存在性不安全感,以及形容词的特殊使用,表明感知超越。

解读

青少年提供了对明显扭曲且几乎难以言表的经历的自然主义描述。这种独特的不规则“BSD语言”在其适当的背景下具有高度意义,表达了第一人称体验改变的信息特征,这对早期检测至关重要。这些特征还可能代表精神病转变的先兆,对临床决策有用。

资金来源

挪威奥斯陆达姆基金会(资助编号2017/FO143368)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8816/9661513/1ea175d9d546/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8816/9661513/1ea175d9d546/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8816/9661513/1ea175d9d546/gr1.jpg

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本文引用的文献

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Clin Neuropsychiatry. 2021 Dec;18(6):293-295. doi: 10.36131/cnfioritieditore20210602.
2
Prevalence and assessment of self-disorders in the schizophrenia spectrum: a systematic review and meta-analysis.精神分裂症谱系中自我障碍的患病率及评估:系统评价和荟萃分析。
Sci Rep. 2022 Jan 21;12(1):1165. doi: 10.1038/s41598-022-05232-9.
3
Self-disorders and psychopathology: a systematic review.自我障碍与精神病理学:系统综述。
通过自然语言处理对临床高危和早期精神病患者自发言语中异常自我体验的差异表达进行定量分析。
Biol Psychiatry Cogn Neurosci Neuroimaging. 2023 Oct;8(10):1005-1012. doi: 10.1016/j.bpsc.2023.06.007. Epub 2023 Jul 5.
Lancet Psychiatry. 2021 Nov;8(11):1001-1012. doi: 10.1016/S2215-0366(21)00097-3.
4
Disordered Selfhood in Schizophrenia and the Examination of Anomalous Self-Experience: Accumulated Evidence and Experience.精神分裂症中的紊乱自我与异常自我体验的检查:累积证据与经验。
Psychopathology. 2021;54(6):275-281. doi: 10.1159/000517672. Epub 2021 Aug 12.
5
Uncovering the realities of delusional experience in schizophrenia: a qualitative phenomenological study in Belgium.揭示精神分裂症妄想体验的现实:比利时的定性现象学研究。
Lancet Psychiatry. 2021 Sep;8(9):784-796. doi: 10.1016/S2215-0366(21)00196-6. Epub 2021 Aug 3.
6
The Self in the Spectrum: A Meta-analysis of the Evidence Linking Basic Self-Disorders and Schizophrenia.自我在光谱中的位置:基本自我障碍与精神分裂症关联证据的元分析。
Schizophr Bull. 2021 Jul 8;47(4):1007-1017. doi: 10.1093/schbul/sbaa201.
7
Understanding Language Abnormalities and Associated Clinical Markers in Psychosis: The Promise of Computational Methods.理解精神病学中的语言异常及相关临床标志物:计算方法的前景。
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8
Double bookkeeping and schizophrenia spectrum: divided unified phenomenal consciousness.双重记账与精神分裂谱系:分裂统一的现象意识。
Eur Arch Psychiatry Clin Neurosci. 2021 Dec;271(8):1513-1523. doi: 10.1007/s00406-020-01185-0. Epub 2020 Sep 8.
9
Prevention of Psychosis: Advances in Detection, Prognosis, and Intervention.预防精神病学:检测、预后和干预的新进展。
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NPJ Schizophr. 2019 Jun 13;5(1):9. doi: 10.1038/s41537-019-0077-9.