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小儿腹股沟手术:使用普通布比卡因的骶管阻滞和腹股沟区域阻滞镇痛效果比较

Pediatric Groin Surgeries: A Comparison of Analgesic Effects of Caudal Block and Inguinal Field Block Using Plain Bupivacaine.

作者信息

Kalu Ukoha Agwu, Odi Temitope O, Taiwo Jones O, Abdur-Rahman Lukman Olajide, Oyewole Ezekiel O, Ibiyeye Taiye T

机构信息

Department of Surgery, Federal Medical Centre, Lokoja, Kogi State, Nigeria.

Department of Surgery, University of Ilorin Teaching Hospital, Ilorin, Kwara State, Nigeria.

出版信息

J West Afr Coll Surg. 2022 Jul-Sep;12(3):96-103. doi: 10.4103/jwas.jwas_146_22. Epub 2022 Oct 6.

Abstract

INTRODUCTION

There is a paucity of studies in the West African sub-region which have compared both the intraoperative and postoperative analgesic effects of caudal block and inguinal field block using plain bupivacaine in groin surgeries in children. The study aimed to compare the duration of analgesia and complications of caudal block and inguinal field block in pediatric groin surgeries.

PATIENTS AND METHODS

This was a prospective, double-blind randomized study conducted at a tertiary health institution in North Central, Nigeria, over a period of 6 months. A total of 74 children scheduled for day case groin surgeries for inguinal hernia, hydrocoele and palpable undescended testis were recruited into the study. The effectiveness of the analgesic effect was assessed by measuring serum cortisol levels before surgery (i.e. baseline at 8am), 5minutes after caudal block or inguinal field block, and 1-hour after surgery. Post-operative pain was determined using FLACC score (Face, Legs, Activity, Crying and Consolability) every 15 minutes till 6 hours after surgery when the patients were discharged home and the caregivers measured the patients' pain scores using the FLACC score every 1 hour to a maximum duration of 10 hours after surgery. Data obtained from the study was entered into the study proforma and analysed using IBM SPSS version 21.0. The value was considered statistically significant at <0.05.

RESULTS

A total of 74 patients were recruited for this study, with 68 males (91.9%) and 6 females (8.1%). The children's age range was 6 months to 7 years, with a mean age of 3.35 ± 1.90 years. The mean basal serum cortisol levels of the caudal block group and inguinal block group were 11.15 ± 5.38 µg/dL and 10.79 ± 4.92µg/d respectively (p-value = 0.767). Five minutes after caudal block, the mean serum cortisol level was 10.50 ± 5.39µg/dL while inguinal field block was 10.63 ± 4.68µg/dL (p-value = 0.288). The mean serum cortisol level obtained one hour after each procedure was 9.34 ± 4.05 µg/dL for the caudal block group and 10.00 ± 3.56 µg/dL in the inguinal field block group with p-value = 0.275.Using the FLACC score, the mean duration of analgesia in caudal block group was 372.00 ± 71.55 minutes and was inguinal field block group was 387.43 ± 62.65 minutes with a p-value = 0.116. There was no anaesthetic technique related complications that was recorded in both caudal block group and inguinal group during the study period.

CONCLUSION

This study demonstrated that caudal block and inguinal field block using plain bupivacaine provided comparable duration of analgesia in paediatric groin surgeries. Therefore, caudal block or inguinal field block using plain bupivacaine should be recommended for both intraoperative and postoperative analgesia in elective paediatric groin surgeries.

摘要

引言

在西非次区域,很少有研究比较在儿童腹股沟手术中使用普通布比卡因进行骶管阻滞和腹股沟区域阻滞的术中及术后镇痛效果。本研究旨在比较小儿腹股沟手术中骶管阻滞和腹股沟区域阻滞的镇痛持续时间及并发症。

患者与方法

这是一项前瞻性、双盲随机研究,在尼日利亚中北部的一家三级医疗机构进行,为期6个月。共有74例计划进行日间腹股沟疝、鞘膜积液和可触及隐睾腹股沟手术的儿童纳入研究。通过在手术前(即上午8点的基线水平)、骶管阻滞或腹股沟区域阻滞后5分钟以及手术后1小时测量血清皮质醇水平来评估镇痛效果。术后每15分钟使用FLACC评分(面部、腿部、活动、哭闹和安慰度)确定疼痛程度,直至术后6小时患者出院,护理人员在术后每1小时使用FLACC评分测量患者疼痛评分,最长持续至术后10小时。从研究中获得的数据录入研究表格,并使用IBM SPSS 21.0版进行分析。P值<0.05被认为具有统计学意义。

结果

本研究共纳入74例患者,其中男性68例(91.9%),女性6例(8.1%)。儿童年龄范围为6个月至7岁,平均年龄为3.35±1.90岁。骶管阻滞组和腹股沟阻滞组的平均基础血清皮质醇水平分别为11.15±5.38µg/dL和10.79±4.92µg/dL(P值=0.767)。骶管阻滞后5分钟,平均血清皮质醇水平为10.50±5.39µg/dL,而腹股沟区域阻滞为10.63±4.68µg/dL(P值=0.288)。各手术1小时后获得的平均血清皮质醇水平,骶管阻滞组为9.34±4.05µg/dL,腹股沟区域阻滞组为10.00±3.56µg/dL,P值=0.275。使用FLACC评分,骶管阻滞组的平均镇痛持续时间为372.00±71.55分钟,腹股沟区域阻滞组为387.43±62.65分钟,P值=0.116。在研究期间,骶管阻滞组和腹股沟组均未记录到与麻醉技术相关的并发症。

结论

本研究表明,在小儿腹股沟手术中,使用普通布比卡因进行骶管阻滞和腹股沟区域阻滞的镇痛持续时间相当。因此,对于择期小儿腹股沟手术的术中及术后镇痛,建议使用普通布比卡因进行骶管阻滞或腹股沟区域阻滞。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/752e/9641741/032dd577c11b/JWACS-12-96-g004.jpg

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