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现实生活中基层医疗环境下老年人的身体、认知和心理健康状况模式以及应对方式的差异。

Patterns of the physical, cognitive, and mental health status of older individuals in a real-life primary care setting and differences in coping styles.

作者信息

Wittlinger Thomas, Bekić Sanja, Guljaš Silva, Periša Vlatka, Volarić Mile, Trtica Majnarić Ljiljana

机构信息

Department of Cardiology, Asklepios Hospital, Goslar, Germany.

Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia.

出版信息

Front Med (Lausanne). 2022 Oct 28;9:989814. doi: 10.3389/fmed.2022.989814. eCollection 2022.

Abstract

BACKGROUND

Physical frailty and cognitive decline are two major consequences of aging and are often in older individuals, especially in those with multimorbidity. These two disorders are known to usually coexist with each other, increasing the risk of each disorder for poor health outcomes. Mental health disorders, anxiety and depression, are common in older people with multimorbidity, in particular those with functional or sensory deficits, and frailty.

PURPOSE

The aim of this study was to show how physical frailty, cognitive impairments and mental disorders, cluster in the real life setting of older primary care (PC) patients, and how these clusters relate to age, comorbidities, stressful events, and coping strategies. Knowing that, could improve risk stratification of older individuals and guide the action plans.

METHODS

Participants were older individuals (≥60, = 263), attenders of PC, independent of care of others, and not suffering from dementia. For screening participants on physical frailty, cognitive impairment, and mental disorders, we used Fried's phenotype model, the Mini-Mental State Examination (MMSE), the Geriatric Anxiety Scale (GAS), and the Geriatric Depression Scale (GDS). For testing participants on coping styles, we used the 14-scale Brief-Coping with Problems Experienced (Brief-COPE) questionnaire. To identify clusters, we used the algorithm . To further describe the clusters, we examined differences in age, gender, number of chronic diseases and medications prescribed, some diagnoses of chronic diseases, the number of life events, body mass index, renal function, expressed as the glomerular filtration rate, and coping styles.

RESULTS

The most appropriate cluster solution was the one with three clusters, that were termed as: functional (FUN; = 139), with predominant frailty or dysfunctional (DFUN; = 81), and with predominant cognitive impairments or cognitively impaired (COG-IMP; = 43). Participants in two pathologic clusters, DFUN and COG-IMP, were in average older and had more somatic diseases, compared to participants in cluster FUN. Significant differences between the clusters were found in diagnoses of osteoporosis, osteoarthritis, anxiety/depression, cerebrovascular disease, and periphery artery disease. Participants in cluster FUN expressed mostly positive reframing coping style. Participants in two pathological clusters were represented with negative coping strategies. Religion and self-blame were coping mechanisms specific only for cluster DFUN; self-distraction only for cluster COG-IMP; and these two latter clusters shared the mechanisms of behavioral disengagement and denial.

CONCLUSION

The research approach presented in this study may help PC providers in risk stratification of older individuals and in getting insights into behavioral and coping strategies of patients with similar comorbidity patterns and functional disorders, which may guide them in preparing prevention and care plans. By providing some insights into the common mechanisms and pathways of clustering frailty, cognitive impairments and mental disorders, this research approach is useful for creating new hypotheses and in accelerating geriatric research.

摘要

背景

身体虚弱和认知衰退是衰老的两个主要后果,在老年人中很常见,尤其是在患有多种疾病的人群中。已知这两种疾病通常相互并存,会增加每种疾病导致不良健康后果的风险。心理健康障碍,如焦虑和抑郁,在患有多种疾病的老年人中很常见,特别是那些有功能或感觉缺陷以及身体虚弱的人。

目的

本研究的目的是展示身体虚弱、认知障碍和精神障碍在老年初级保健(PC)患者的现实生活环境中是如何聚集的,以及这些聚集如何与年龄、合并症、应激事件和应对策略相关。了解这些情况可以改善对老年人的风险分层并指导行动计划。

方法

参与者为年龄≥60岁的老年人(n = 263),是初级保健的就诊者,能够自理且未患痴呆症。为了筛查参与者的身体虚弱、认知障碍和精神障碍,我们使用了弗里德表型模型、简易精神状态检查表(MMSE)、老年焦虑量表(GAS)和老年抑郁量表(GDS)。为了测试参与者的应对方式,我们使用了14项的《应对问题经验简表》(Brief - COPE)问卷。为了识别聚类,我们使用了该算法。为了进一步描述这些聚类,我们检查了年龄、性别、慢性病数量和所开药物、一些慢性病诊断、生活事件数量、体重指数、肾功能(以肾小球滤过率表示)以及应对方式的差异。

结果

最合适的聚类解决方案是分为三个聚类,分别称为:功能良好型(FUN;n = 139),以身体虚弱或功能失调为主(DFUN;n = 81),以及以认知障碍为主或认知受损型(COG - IMP;n = 43)。与FUN聚类中的参与者相比,DFUN和COG - IMP这两个病理聚类中的参与者平均年龄更大且患有更多躯体疾病。在骨质疏松症、骨关节炎、焦虑/抑郁、脑血管疾病和外周动脉疾病的诊断方面,聚类之间存在显著差异。FUN聚类中的参与者大多表现出积极的重新构建应对方式。两个病理聚类中的参与者以消极应对策略为主。宗教和自责是仅DFUN聚类特有的应对机制;自我分心是仅COG - IMP聚类特有的;而后两个聚类共有行为脱离和否认的机制。

结论

本研究中提出的研究方法可能有助于初级保健提供者对老年人进行风险分层,并深入了解具有相似合并症模式和功能障碍患者的行为和应对策略,这可能指导他们制定预防和护理计划。通过深入了解虚弱、认知障碍和精神障碍聚集的一些共同机制和途径,这种研究方法有助于提出新的假设并加速老年医学研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/edb7/9650321/ab48dc15bc45/fmed-09-989814-g0001.jpg

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