Loike John D, Flaum Rabbi Tzvi
Interim Director of Bioethics, School of Health Sciences and Practice, New York Medical College-Associated with Touro University, Valhalla, NY, USA.
Professor of Biology, Touro University, New York, NY, USA.
Rambam Maimonides Med J. 2022 Oct 27;13(4):e0029. doi: 10.5041/RMMJ.10487.
Clustered regularly interspaced short palindromic repeats (CRISPR) gene editing is an innovative and potentially game-changing biotechnology that can potentially reverse DNA mutations in a tissue-specific manner. In addition, CRISPR is being targeted for xenotransplantation, for increasing human longevity, in animal breeding, and in plant science. However, there are many ethical challenges that emerge from CRISPR technology. This article discusses several positions that relate to these ethical challenges from a Jewish legal perspective. In addition, we present several other applications of CRISPR technology that lack a defined Jewish legal precedent and require rabbinical scholars to address and resolve them in the future.
成簇规律间隔短回文重复序列（CRISPR）基因编辑是一项创新的、可能改变游戏规则的生物技术，它有可能以组织特异性方式逆转DNA突变。此外，CRISPR正被用于异种移植、延长人类寿命、动物育种和植物科学领域。然而，CRISPR技术引发了许多伦理挑战。本文从犹太法律的角度探讨了与这些伦理挑战相关的几种立场。此外，我们还介绍了CRISPR技术的其他一些应用，这些应用缺乏明确的犹太法律先例，需要拉比学者在未来加以处理和解决。
