Farhangian Zohre, Alaghehmand Homayoon, Tashakkorian Hamed, Mokhtarpour Faraneh, Davoodabadi Abolfazl
Department Operative of Dentistry, Faculty of Dentistry, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Dental Materials Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.
Dent Res J (Isfahan). 2022 Sep 26;19:81. eCollection 2022.
Graphene oxide (GO), a product of graphite, is a candidate for nano-reinforcing cement-based materials due to its good water dispersibility and excellent mechanical properties. On the other hand, zinc oxide (ZnO) is well-known for its antibacterial characteristics as well. Therefore, we aimed to evaluate the impacts of adding ZnO and GO nanoparticles on the antibacterial properties of flowable composites.
In this, experimental study was designated into five groups containing: (1) no nanoparticles as control group, (2) 1 wt.% ZnO nanoparticle, (3) 1 wt.% GO, (4) 1 wt.% physical compound of ZnO and GO, and (5) 1 wt.% chemical compound of ZnO and GO. The antibacterial properties of composite resin discs were evaluated by direct contact test. Data were analyzed using a one-way analysis of variance, followed by Tukey' tests ( = 0.05).
colony counting in the first 24 h showed the least growth rate in the chemical compound group (2.2 × 10). However, in 7 days, the least colony number was observed in the GO group (2 × 10). Moreover, the physical compound showed the least bacterial adhesion.
Adding GO alone to composites, compared to adding ZnO or physical and chemical compounds of GO-ZnO, was more helpful to increase the antimicrobial characteristics.
氧化石墨烯(GO)是石墨的一种产物,因其良好的水分散性和优异的机械性能,是纳米增强水泥基材料的候选材料。另一方面,氧化锌(ZnO)也因其抗菌特性而闻名。因此,我们旨在评估添加ZnO和GO纳米颗粒对可流动复合材料抗菌性能的影响。
在本实验研究中,分为五组,包括:(1)不添加纳米颗粒作为对照组,(2)1 wt.% ZnO纳米颗粒,(3)1 wt.% GO,(4)1 wt.% ZnO和GO的物理复合物,以及(5)1 wt.% ZnO和GO的化学复合物。通过直接接触试验评估复合树脂圆盘的抗菌性能。数据采用单因素方差分析,随后进行Tukey检验(α = 0.05)。
前24小时的菌落计数显示,化学复合物组的生长速率最低(2.2×10)。然而,在7天时,GO组的菌落数最少(2×10)。此外,物理复合物的细菌粘附最少。
与添加ZnO或GO-ZnO的物理和化学复合物相比,单独向复合材料中添加GO更有助于提高抗菌特性。