Nestlé Institute of Health Sciences, Nestlé Research, Société des Produits Nestlé S.A., Vers-chez-les-Blanc, 1000 Lausanne, Switzerland.
Nestlé Institute of Health Sciences, Nestlé Research, Société des Produits Nestlé S.A., 1015 Lausanne, Switzerland.
Nutrients. 2022 Nov 8;14(22):4719. doi: 10.3390/nu14224719.
Subclinical mastitis (SCM) is an inflammatory state of the lactating mammary gland, which is asymptomatic and may have negative consequences for child growth. The objectives of this study were to: (1) test the association between the dietary inflammatory index (DII®) and SCM and (2) assess the differences in nutrient intakes between women without SCM and those with SCM. One hundred and seventy-seven women with available data on human milk (HM) sodium potassium ratio (Na:K) and dietary intake data were included for analysis. Multivariable logistic regression was used to examine the association between nutrient intake and the DII score in relation to SCM. Women without SCM had a lower median DII score (0.60) than women with moderate (1.12) or severe (1.74) SCM (p < 0.01). A one-unit increase in DII was associated with about 41% increased odds of having SCM, adjusting for country and mode of delivery, p = 0.001. Women with SCM had lower mean intakes of several anti-inflammatory nutrients. We show for the first time exploratory evidence that SCM may be associated with a pro-inflammatory diet and women with SCM have lower intakes of several antioxidant and anti-inflammatory nutrients.
隐性乳腺炎（SCM）是一种哺乳期乳腺的炎症状态，其无症状，但可能对儿童生长产生负面影响。本研究的目的是：（1）检验饮食炎症指数（DII®）与 SCM 的相关性；（2）评估无 SCM 妇女与有 SCM 妇女的营养素摄入量差异。共有 177 名妇女的母乳（HM）钠钾比（Na:K）和饮食摄入数据可用，纳入进行分析。多变量逻辑回归用于检验营养素摄入与 DII 评分与 SCM 之间的关系。无 SCM 的妇女的 DII 评分中位数（0.60）低于中度（1.12）或重度（1.74）SCM 的妇女（p < 0.01）。校正国家和分娩方式后，DII 增加一个单位与 SCM 的发生几率增加约 41%有关，p = 0.001。患有 SCM 的妇女的几种抗炎营养素的平均摄入量较低。我们首次探索性地证明 SCM 可能与促炎饮食有关，并且患有 SCM 的妇女的几种抗氧化和抗炎营养素摄入量较低。
