Guo Dongling, Meng Jiaqi, Zhang Keke, He Wenwen, Ma Shiyu, Lu Zhong-Lin, Lu Yi, Zhu Xiangjia
Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai, 200031, China.
NHC Key Laboratory of Myopia, Fudan University, Shanghai, China.
Eye Vis (Lond). 2022 Dec 1;9(1):45. doi: 10.1186/s40662-022-00317-y.
Quick contrast sensitivity function (qCSF) method is an advanced quick method for contrast sensitivity function (CSF) evaluation. This study evaluated the contrast sensitivity (CS) of eyes undergoing cataract surgery with multifocal intraocular lens (IOL) implantation and its tolerance to IOL tilt and IOL decentration using the qCSF method.
Patients undergoing uneventful phacoemulsification and a trifocal IOL (Zeiss AT LISA tri 839MP, Carl Zeiss, Germany) or an extended depth-of-focus (EDOF) IOL (Tecnis Symfony ZXR00, Johnson & Johnsons, USA) implantation were included. Monocular contrast sensitivity was measured using the qCSF method at one month post-surgery. IOL tilt and decentration were measured using an optical aberrometer (OPD-Scan III, NIDEK, Japan).
Seventy-two patients/eyes with the 839MP IOL and 64 patients/eyes with the ZXR00 IOL were included. Area under the log CSF (AULCSF) and CS acuity did not differ significantly between the two groups. The ZXR00 IOL group showed better CS at 1 cpd (1.137 ± 0.164 vs. 1.030 ± 0.183 logCS) and 1.5 cpd (1.163 ± 0.163 vs. 1.071 ± 0.161 logCS), while the 839MP IOL group had better CS at 6 cpd (0.855 ± 0.187 vs. 0.735 ± 0.363 logCS). In the 839MP IOL group, all CSF metrics were negatively correlated with IOL tilt (all P < 0.05), while in the ZXR00 IOL group, the CS at 3 cpd had no significant correlation with IOL tilt (P > 0.05). Among myopic eyes, fewer CSF metrics were negatively correlated with IOL tilt in the ZXR00 IOL group than in the 839MP IOL group. No significant correlation was found between CSF metrics and IOL decentration.
The ZXR00 and the 839MP IOL groups presented comparable CSF. CS was negatively correlated with IOL tilt, instead of decentration in multifocal IOLs, particularly among myopic eyes. The ZXR00 IOL had better tolerance to IOL tilt in myopic eyes.
快速对比敏感度函数(qCSF)方法是一种先进的用于评估对比敏感度函数(CSF)的快速方法。本研究使用qCSF方法评估了接受多焦点人工晶状体(IOL)植入白内障手术的眼睛的对比敏感度(CS)及其对IOL倾斜和IOL偏心的耐受性。
纳入接受顺利的超声乳化手术并植入三焦点IOL(蔡司AT LISA tri 839MP,德国卡尔蔡司公司)或扩展景深(EDOF)IOL(Tecnis Symfony ZXR00,美国强生公司)的患者。术后1个月使用qCSF方法测量单眼对比敏感度。使用光学像差仪(OPD-Scan III,日本尼德克公司)测量IOL倾斜和偏心。
纳入了72例使用839MP IOL的患者/眼和64例使用ZXR00 IOL的患者/眼。两组之间的对数CSF下面积(AULCSF)和CS视力无显著差异。ZXR00 IOL组在1 cpd(1.137±0.164 vs. 1.030±0.183 logCS)和1.5 cpd(1.163±0.163 vs. 1.071±0.161 logCS)时显示出更好的CS,而839MP IOL组在6 cpd时具有更好的CS(0.855±0.187 vs. 0.735±0.363 logCS)。在839MP IOL组中,所有CSF指标均与IOL倾斜呈负相关(所有P<0.05),而在ZXR00 IOL组中,3 cpd时的CS与IOL倾斜无显著相关性(P>0.05)。在近视眼中,ZXR00 IOL组中与IOL倾斜呈负相关的CSF指标比839MP IOL组少。未发现CSF指标与IOL偏心之间存在显著相关性。
ZXR00和839MP IOL组的CSF相当。CS与IOL倾斜呈负相关,而不是与多焦点IOL的偏心相关,尤其是在近视眼中。ZXR00 IOL在近视眼中对IOL倾斜具有更好的耐受性。