活性 DNA 去甲基化会损害 DNA。
Active DNA demethylation damages DNA.
机构信息
Division of Signaling and Gene Expression, La Jolla Institute for Immunology, La Jolla, CA, USA.
Sanford Consortium for Regenerative Medicine, La Jolla, CA, USA.
出版信息
Science. 2022 Dec 2;378(6623):948-949. doi: 10.1126/science.adf3171. Epub 2022 Dec 1.
Abstract
Active DNA demethylation maintains enhancer activity in nonproliferating cells but can damage DNA.
摘要
活性 DNA 去甲基化在非增殖细胞中维持增强子活性，但可能会损害 DNA。
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