Sawada Ryoko, Shinoda Yusuke, Niimi Aya, Nakagawa Tohru, Ikegami Masachika, Kobayashi Hiroshi, Tanaka Sakae, Homma Yukio, Haga Nobuhiko
Department of Orthopedic Surgery, The University of Tokyo Hospital, Tokyo, Japan.
Department of Rehabilitation Medicine, The University of Tokyo Hospital, Tokyo, Japan.
Case Rep Urol. 2017;2017:7830207. doi: 10.1155/2017/7830207. Epub 2017 Jul 3.
Metastasis may occur in any bone but more commonly occurs in the spine, pelvis, or other axial bones. Metastasis in peripheral bones located distal to the elbow or knee, so-called acrometastasis, is rare. Although the mechanism of acrometastasis development is not completely understood, it is thought to be the result of a massive dissemination of cancer cells; thus the prognosis of patients with acrometastasis is relatively poor. Here, we report the case of renal pelvic cancer with multiple acrometastases in both the upper and lower extremities without axial bone metastasis in a 68-year-old man. After two regimens of chemotherapy, he suffered from pain on his wrist and ankle and swelling and hemorrhage of his toe. He had no axial bone metastasis by CT but was diagnosed with multiple acrometastases by plain radiographs. Radiation therapy and disarticulation of the left big toe at the metacarpal-phalangeal joint were performed and his pain and hemorrhage were successfully controlled. Although acrometastasis from renal pelvic cancer is very rare, we should recognize that acrometastasis might occur which exists outside of the CT scanning field.
转移可发生于任何骨骼,但更常见于脊柱、骨盆或其他中轴骨。发生于肘部或膝部远端的外周骨转移,即所谓的肢端转移,较为罕见。尽管肢端转移发生的机制尚未完全明确,但一般认为这是癌细胞大量播散的结果;因此,肢端转移患者的预后相对较差。在此,我们报告一例68岁男性肾盂癌患者,其双上肢和双下肢均出现多发肢端转移,而中轴骨未发生转移。在接受两个疗程的化疗后,他出现手腕和脚踝疼痛,以及脚趾肿胀和出血。CT检查显示他没有中轴骨转移,但X线平片诊断为多发肢端转移。我们对其进行了放射治疗,并在掌指关节处对左大足趾进行了关节离断术,成功控制了他的疼痛和出血。尽管肾盂癌的肢端转移非常罕见,但我们应认识到可能会出现CT扫描范围外的肢端转移。