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用于出院计划的深度学习和迁移学习的神经外科住院患者结局预测

Neurosurgery inpatient outcome prediction for discharge planning with deep learning and transfer learning.

作者信息

Lam Lydia, Lam Antoinette, Bacchi Stephen, Abou-Hamden Amal

机构信息

Adelaide Medical School, University of Adelaide, Adelaide, SA, Australia.

Royal Adelaide Hospital, Adelaide, SA, Australia.

出版信息

Br J Neurosurg. 2025 Feb;39(1):110-114. doi: 10.1080/02688697.2022.2151565. Epub 2022 Dec 2.

Abstract

INTRODUCTION

Deep learning may be able to assist with the prediction of neurosurgical inpatient outcomes. The aims of this study were to investigate deep learning and transfer learning in the prediction of several inpatient outcomes including timing of discharge and discharge destination.

METHOD

Data were collected on consecutive neurosurgical admissions from existing databases over a 15-month period. Following pre-processing artificial neural networks were applied to admission notes and ward round notes to predict four inpatient outcomes. Models were developed on the training dataset, before being tested on a hold-out test dataset and a validation dataset.

RESULTS

1341 individual admissions were included in the study. Using transfer learning and an artificial neural network an area under the receiver operator curve (AUC) of 0.81 and 0.80 on the derivation and validation datasets was able to be achieved for the prediction of discharge within the next 48 hours using daily ward round notes. This result is in comparison to an AUC of 0.71 and 0.68 using an artificial neural network without transfer learning for the same outcome. When the artificial neural network with transfer learning was applied to the other outcomes AUC of 0.72, 0.93 and 0.83 was achieved on the validation datasets for predicting discharge within the next 7 days, survival to discharge and discharge to home as a destination.

CONCLUSIONS

Deep learning may predict inpatient neurosurgery outcomes from free-text medical data. Recurrent predictions with ward round notes enable the use of information obtained throughout hospital admissions in these estimates.

摘要

引言

深度学习或许能够辅助预测神经外科住院患者的预后。本研究旨在探讨深度学习和迁移学习在预测包括出院时间和出院去向等多项住院患者预后方面的应用。

方法

在15个月的时间里,从现有数据库中收集连续神经外科住院患者的数据。经过预处理后,将人工神经网络应用于入院记录和查房记录,以预测四项住院患者预后情况。模型在训练数据集上开发,然后在保留测试数据集和验证数据集上进行测试。

结果

本研究纳入了1341例个体住院病例。使用迁移学习和人工神经网络,利用每日查房记录预测未来48小时内出院情况时,在推导数据集和验证数据集上的受试者操作特征曲线下面积(AUC)分别达到0.81和0.80。相比之下,对于相同结局,使用无迁移学习的人工神经网络时,AUC分别为0.71和0.68。当将具有迁移学习的人工神经网络应用于其他结局时,在验证数据集上预测未来7天内出院、出院时存活以及出院目的地为回家的AUC分别为0.72、0.93和0.83。

结论

深度学习或许能够从自由文本医学数据中预测住院神经外科患者的预后。通过查房记录进行反复预测,能够在这些评估中利用整个住院期间获得的信息。

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