College of Safety Science and Engineering, Xi'an University of Science and Technology, Xi'an, 710054, China.
Division Animal and Human Health Engineering, Department of Biosystems (BIOSYST), KU Leuven, Kasteelpark Arenberg 30, BE-3001, Leuven, Belgium.
Comput Biol Med. 2022 Dec;151(Pt B):106351. doi: 10.1016/j.compbiomed.2022.106351. Epub 2022 Nov 26.
A 7-segment and 29-node numerical hand-glove/mitten model was developed to simulate human hand physiological responses in various cold environments. To validate the model, simulated skin temperatures were compared to data from published literature and human trials conducted at -20, -40, and -60 °C. Results demonstrated that the model could reasonably predict cold-induced vasodilation (CIVD) responses at 0 °C temperature. At -20 °C, the model predicted skin temperature with the root mean square deviation (RMSD) falling within the measurement standard deviation (SD) for both the entire and local hand except for the posterior hand. At -40 and -60 °C, the model could predict the trend of the skin temperatures of the whole/local hand, but the RMSD was larger than the SD for the majority of predictions. A parametric analysis revealed that the palm and posterior hand had higher skin temperatures than the fingers, while the thumb had the lowest skin temperature of the fingers in all simulated cases except the case with a 3.5 clo mitten at -60 °C. The proposed numerical hand-glove/mitten model could reasonably predict local hand physiological responses in three extremely cold environments and provides fundamental knowledge for cold stress prediction and protective glove development, thereby improving the safety and health of industrial workers, firefighters, first responders, and troops.
开发了一个 7 段 29 节点的数值手套/连指手套模型,以模拟各种寒冷环境下人手的生理反应。为了验证该模型,模拟皮肤温度与已发表文献和在-20、-40 和-60°C 进行的人体试验数据进行了比较。结果表明,该模型可以合理预测 0°C 温度下的冷诱导血管扩张(CIVD)反应。在-20°C 时,模型预测的皮肤温度,除了后手之外,整个和局部手部的均方根偏差(RMSD)都在测量标准差(SD)范围内。在-40 和-60°C 时,模型可以预测整个/局部手部皮肤温度的趋势,但对于大多数预测,RMSD 大于 SD。参数分析表明,手掌和后手的皮肤温度高于手指,而除了-60°C 时戴 3.5 克罗手套的情况外,拇指的皮肤温度在所有模拟情况下都是手指中最低的。所提出的数值手套/连指手套模型可以合理地预测三种极寒环境下的手部局部生理反应,为寒冷应激预测和防护手套开发提供了基础知识,从而提高了工业工人、消防员、急救人员和部队的安全性和健康水平。