免疫功能低下患者中的猴痘及其广泛临床谱：两例病例报告
Monkeypox and its broad clinical spectrum in immunocompromised patients: Two case reports.
作者信息
Martínez Carlos Adrián Pérez, Flores Gustavo Antolin Silva, Santamaría Fernando Padilla, Franco Lucero Maya, Cano Floribel Ferman, Fierro Luis Alberto García, Cárdenas Carlos Daniel Sánchez, Magaña América Citlali Hernández
机构信息
Department of Internal Medicine, General Hospital "Ajusco Medio". Secretary of Health of Mexico City, Mexico City, Mexico.
Dermatology Department, Specialty Hospital "Antonio Fraga Mouret", "La Raza" National Medical Center. Mexican Social Security Institute, Mexico City, Mexico.
出版信息
IDCases. 2022 Nov 25;31:e01651. doi: 10.1016/j.idcr.2022.e01651. eCollection 2023.
Monkeypox is the latest reemerging zoonosis worldwide. Anyone is susceptible to contracting this infection; however, the clinical presentation may be atypical in a particularly vulnerable group that identifies as men who have sex with men. Herein, we present two cases of patients diagnosed with monkeypox infection, both of whom were also co-infected with human immunodeficiency virus (HIV) and exhibited different degrees of immunosuppression. Notably, the clinical presentations differed significantly. Patients co-infected with HIV are prone to develop clinical features ranging from barely visible lesions to severe or even fatal disease.
猴痘是全球最新出现的人畜共患病。任何人都易感染这种疾病；然而，在一个特定的弱势群体——自认为是男男性行为者中，临床表现可能不典型。在此，我们报告两例被诊断为猴痘感染的患者，他们均同时感染了人类免疫缺陷病毒（HIV），并表现出不同程度的免疫抑制。值得注意的是，两者的临床表现差异显著。合并感染HIV的患者容易出现从几乎看不见的皮损到严重甚至致命疾病等一系列临床特征。
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