巴西圣保罗州城区内新热带蝙蝠汉坦病毒感染的血清学证据。
Serological evidence of hantavirus infection in neotropical bats in an urban area of São Paulo State, Brazil.
机构信息
Virology Research Center, Ribeirão Preto School of Medicine, University of São Paulo, Ribeirão Preto, 140490-900, São Paulo, Brazil.
Departamento de Vigilância em Saúde, Prefeitura Municipal de Ribeirão Preto, Ribeirão Preto, 14061-710, São Paulo, Brazil.
出版信息
Trans R Soc Trop Med Hyg. 2023 Apr 3;117(4):297-300. doi: 10.1093/trstmh/trac111.
BACKGROUND
Although hantaviruses have long been associated with rodents, they are also described in other mammalian hosts, such as shrews, moles and bats. Hantaviruses associated with bats have been described in Asian, European and Brazilian species of bats. As these mammals represent the second major mammalian order, and they are the major mammals that inhabit urban areas, it is extremely important to maintain a viral surveillance in these animals. Our aim was to conduct serosurveillance in bats in an urban area in the city of Ribeirão Preto, São Paulo State, Brazil, to contribute to the information about hantaviruses circulation in bats.
METHODS
We analyzed samples from 778 neotropical bat specimens classified into 21 bat species and four different families collected in the urban area of Ribeirão Preto city, from 2014 to 2019 by an ELISA for the detection of IgG antibodies against orthohantavirus.
RESULTS
We detected IgG-specific antibodies against the nucleoprotein of orthohantavirus in 0.9% (7/778) bats tested, including four Molossus molossus (Pallas' Free-tailed Bat), two Glossophaga soricina (Pallas's Long-tongued Bat) and one Eumops glaucinus (Wagner's mastiff bat).
CONCLUSIONS
Overall, our results show the first serological evidence of hantavirus infection in three common bat species in urban areas.
背景
虽然汉坦病毒长期以来一直与啮齿动物有关，但它们也存在于其他哺乳动物宿主中，如鼩鼱、鼹鼠和蝙蝠。与蝙蝠相关的汉坦病毒已在亚洲、欧洲和巴西的蝙蝠物种中被描述。由于这些哺乳动物代表了第二大哺乳动物目，并且它们是主要栖息在城市地区的哺乳动物，因此在这些动物中保持病毒监测极为重要。我们的目的是在巴西圣保罗州里贝朗普雷托市的一个城市地区对蝙蝠进行血清学监测，以提供有关蝙蝠中汉坦病毒传播的信息。
方法
我们分析了 2014 年至 2019 年从里贝朗普雷托城市地区收集的 778 只新热带蝙蝠标本的样本，这些蝙蝠标本分为 21 种蝙蝠和四个不同的科，通过 ELISA 检测针对 orthohantavirus 的 IgG 抗体进行分析。
结果
我们在检测的 778 只蝙蝠中检测到了 0.9%（7/778）的 orthohantavirus 核蛋白 IgG 特异性抗体，包括 4 只 Molossus molossus（Pallas' Free-tailed Bat）、2 只 Glossophaga soricina（Pallas's Long-tongued Bat）和 1 只 Eumops glaucinus（Wagner's mastiff bat）。
结论
总的来说，我们的结果首次表明在城市地区的三种常见蝙蝠物种中存在汉坦病毒感染的血清学证据。
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