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乳腺癌幸存者的生活质量与年龄、手术类型和首次治疗后时间的关系。

Quality of Life in Breast Cancer Survivors in Relation to Age, Type of Surgery and Length of Time since First Treatment.

机构信息

Department of Sports, Isabel I University, 09003 Burgos, Spain.

Division of Biological Sciences and Health, University of Sonora, Hermosillo 83000, Mexico.

出版信息

Int J Environ Res Public Health. 2022 Dec 4;19(23):16229. doi: 10.3390/ijerph192316229.

Abstract

(1) Background: Quality of life assessment is a critical aspect of breast cancer patient outcomes, as diagnosis, prognosis and treatment can have a major impact on quality of life. The aim of this study was to describe the characteristics of the sample and to verify the relationship between quality of life (QOL) in women diagnosed with breast cancer (BC) and their age, type or surgery and time since treatment; (2) Methods: a cross-sectional, descriptive study was conducted with 183 women diagnosed with BC, aged 30−80 years in Mexico. Women’s QOL was assessed using two questionnaires, The European Organization for Research and Treatment of Cancer-Quality of Life Core Questionnaire (EORTC QLQ-C30) and The Breast Cancer Module (EORTC QLQ-BR23). (3) Results: the results show significant differences in several items when the variable age is taken into account, indicating that younger women have poorer social and sexual function, as well as poorer sexual enjoyment and lower expectations of the future. The type of surgery also indicates a significantly better QOL in those women who receive conservative treatment versus a mastectomy; the time elapsed since surgery does not show any significant results, except for sexual functioning and breast-related symptoms where >5 years implies better scores on the items. (4) Conclusions: in conclusion, it is important to take into account the characteristics of women with BC, particularly at the time of treatment, in order to mitigate the impact of the disease on their QOL with the help of a multidisciplinary team.

摘要

(1) 背景:生活质量评估是乳腺癌患者结局的一个关键方面,因为诊断、预后和治疗都可能对生活质量产生重大影响。本研究的目的是描述样本的特征,并验证生活质量(QOL)与女性乳腺癌(BC)诊断年龄、类型或手术以及治疗后时间之间的关系;(2) 方法:这是一项在墨西哥进行的横断面、描述性研究,纳入了 183 名年龄在 30-80 岁之间的 BC 女性患者。使用欧洲癌症研究与治疗组织生活质量核心问卷(EORTC QLQ-C30)和乳腺癌模块(EORTC QLQ-BR23)对女性的 QOL 进行评估;(3) 结果:结果表明,在考虑年龄这一变量时,几个项目存在显著差异,这表明年轻女性的社会和性功能较差,性享受较差,对未来的期望较低。手术类型也表明,与接受乳房切除术的女性相比,接受保守治疗的女性 QOL 显著更好;手术结束后时间没有显示出任何显著结果,除了性功能和乳房相关症状,其中>5 年意味着这些项目的得分更好;(4) 结论:总之,重要的是要考虑到 BC 女性的特征,特别是在治疗时,以便通过多学科团队帮助减轻疾病对其 QOL 的影响。

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