Department of Organisation and Economics of Pharmacy, Faculty of Pharmacy, Medical University of Plovdiv, 4002 Plovdiv, Bulgaria.
Curr Oncol. 2024 Jul 25;31(8):4178-4191. doi: 10.3390/curroncol31080312.
Breast cancer is the leading cause of cancer-related death in women worldwide and the fifth most common cause of cancer death overall. Most women with breast cancer have a good prognosis if the cancer is detected at an early stage and the patients have access to the appropriate treatment and disease management. This study aims to evaluate the impact of pharmacist-led interventions on breast cancer management and health outcomes. A literature review was carried out through the scientific databases PubMed, Scopus, and Web of Science using predefined keywords. Only full-text original articles written in English that investigated the role of the pharmacist in the management of breast cancer were included in the final analysis. No publication date limits were set. A total of 1625 articles were retrieved from the electronic databases, of which 14 met the inclusion criteria. The current scoping review consists of different study types, including randomized controlled trials, cross-sectional studies, pre-post studies, retrospective cohort studies, quality improvement projects, case-control studies, and one pharmacoeconomic study. Pharmacists commonly provided the following interventions: consultations regarding chemotherapy treatment, risk assessment and patient education, adverse drug reactions and drug-drug interactions detection, and adherence assessment. This scoping review highlights the beneficial effects of the involvement of pharmacists in breast cancer management, such as better quality of life, reduced drug interaction risk, greater adherence rates, and improved patient knowledge. This confirms the importance of including the pharmacist in the oncology team caring for patients with breast cancer.
乳腺癌是全球女性癌症相关死亡的主要原因，也是总体上癌症死亡的第五大常见原因。如果癌症在早期被发现，并且患者能够获得适当的治疗和疾病管理，大多数患有乳腺癌的女性预后良好。本研究旨在评估药剂师主导的干预措施对乳腺癌管理和健康结果的影响。通过科学数据库 PubMed、Scopus 和 Web of Science 进行了文献回顾，使用了预定义的关键字。只有全文原始文章，以英文书写，调查药剂师在乳腺癌管理中的作用的文章才被纳入最终分析。未设置出版日期限制。从电子数据库中检索到 1625 篇文章，其中 14 篇符合纳入标准。目前的范围综述包括不同类型的研究，包括随机对照试验、横断面研究、前后研究、回顾性队列研究、质量改进项目、病例对照研究和一项药物经济学研究。药剂师通常提供以下干预措施：关于化疗治疗、风险评估和患者教育、药物不良反应和药物相互作用检测以及药物依从性评估的咨询。本范围综述强调了药剂师参与乳腺癌管理的有益效果，例如提高生活质量、降低药物相互作用风险、提高药物依从性和改善患者知识。这证实了在为乳腺癌患者提供护理的肿瘤团队中包括药剂师的重要性。
