Muñoz-Barba Daniel, Soto-Moreno Alberto, Haselgruber-de Francisco Sofía, Sánchez-Díaz Manuel, Arias-Santiago Salvador
Dermatology Unit, Hospital Universitario Virgen de las Nieves, IBS Granada, Granada, Spain; Dermatology Department, School of Medicine, University of Granada, Granada, Spain.
Dermatology Unit, Hospital Universitario Virgen de las Nieves, IBS Granada, Granada, Spain; Dermatology Department, School of Medicine, University of Granada, Granada, Spain; Institute of Biosanitary Research IBS, Granada, Spain.
Acta Derm Venereol. 2025 Sep 10;105:adv43039. doi: 10.2340/actadv.v105.43039.
Alopecia areata is a prevalent autoimmune condition causing non-scarring alopecia, with significant impacts on quality of life. However, the long-term effects on major life-changing decisions remain understudied. A cross-sectional study was performed including patients with alopecia areata who attended the Dermatology Department of the Virgen de las Nieves University Hospital. Patients were asked to complete questionnaires to assess the impact of alopecia areata on major life-changing decisions and quality of life. A total of 70 patients were included: 71% were female and 29% were male. The mean age was 38.70 (SD 14.32). The most affected major life-changing decisions were couple relationships and dressing; followed by job performance, social relationships, lifestyle changes, and sports practice. Female gender, higher therapeutic burden, or Dermatology Life Quality Index scores, and lower World Health Organization Five Well Being Index rating were significantly associated with greater major life-changing decisions impairment (p < 0.05). Disease severity and duration did not correlate with increased impact in most major life-changing decisions (p > 0.10). In conclusion, there are some major life-changing decisions that appear to be significantly affected in patients with alopecia areata. The identification of factors associated such us female gender, therapeutic burden, or alterations in mental well-being is crucial to explore and limit the long-term negative effects of the disease.
斑秃是一种常见的自身免疫性疾病，可导致非瘢痕性脱发，对生活质量有重大影响。然而，其对重大生活决策的长期影响仍未得到充分研究。我们进行了一项横断面研究，纳入了就诊于拉斯涅韦斯圣母大学医院皮肤科的斑秃患者。患者被要求填写问卷，以评估斑秃对重大生活决策和生活质量的影响。共纳入70例患者：71%为女性，29%为男性。平均年龄为38.70岁（标准差14.32）。受影响最大的重大生活决策是恋爱关系和着装；其次是工作表现、社交关系、生活方式改变和体育锻炼。女性、更高的治疗负担或皮肤病生活质量指数得分，以及更低的世界卫生组织五福指数评分与更大的重大生活决策受损显著相关（p<0.05）。疾病严重程度和病程与大多数重大生活决策中影响的增加无关（p>0.10）。总之，斑秃患者的一些重大生活决策似乎受到了显著影响。识别诸如女性性别、治疗负担或心理健康改变等相关因素对于探索和限制该疾病的长期负面影响至关重要。
