Department of Central Laboratory, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing Maternal and Child Health Care Hospital, Beijing 100026, China.
Guangdong Provincial Engineering Technology Research Center of Environmental and Health Risk Assessment, Department of Occupational and Environmental Health, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China.
Int J Environ Res Public Health. 2022 Dec 6;19(23):16374. doi: 10.3390/ijerph192316374.
Background: The aim of this study was to assess the association between pet ownership and threatened abortion (TA) in pregnant Chinese women. Materials and Methods: We enrolled pregnant women from 18 provinces and autonomous regions across China between November 2017 and December 2020. Participants were grouped based on the presence or absence of pet ownership. Pet owners were further sub-grouped based on the presence or absence of close contact with their pets. Pet species included cats, dogs, and both. Generalised linear mixed models, with province as a random effect, were used to estimate the associations between pet ownership and TA. Results: Pet ownership, whether or not one had close contact with pets, was associated with greater odds of TA (OR: 1.30, 95% CI: 1.21, 1.40). Keeping pet cats (OR: 1.24, 95% CI: 1.11, 1.40), dogs (OR: 1.29, 95% CI: 1.18, 1.41), or both cats and dogs (OR: 1.36, 95% CI: 1.04, 1.68) during pregnancy were all risk factors for TA. We observed significant group differences (p for difference < 0.05) in pre-pregnancy body mass index, education levels, and annual household income. Conclusions: Cat or dog ownership during pregnancy was associated with an increased risk of TA, especially among overweight, less educated, or lower-income participants.
本研究旨在评估宠物拥有与中国孕妇先兆流产（TA）之间的关联。
我们于 2017 年 11 月至 2020 年 12 月期间，在中国 18 个省和自治区招募了孕妇。参与者根据是否拥有宠物进行分组。宠物主人根据是否与宠物密切接触进一步分组。宠物种类包括猫、狗，或两者兼有。采用广义线性混合模型，以省份为随机效应，估计宠物拥有与 TA 之间的关联。
无论是否与宠物密切接触，宠物拥有与 TA 的发生几率增加相关（OR：1.30，95%CI：1.21，1.40）。在怀孕期间养宠物猫（OR：1.24，95%CI：1.11，1.40）、宠物狗（OR：1.29，95%CI：1.18，1.41）或两者都养（OR：1.36，95%CI：1.04，1.68）均是 TA 的危险因素。我们观察到，孕妇在孕前体质量指数、教育水平和家庭年收入方面存在显著的组间差异（p 差值<0.05）。
怀孕期间养猫或养狗与 TA 的发生风险增加相关，特别是在超重、受教育程度较低或收入较低的参与者中。
