Caminal Josep Maria, Lorenzo Daniel, Gutierrez Cristina, Slocker Andrea, Piulats Josep Maria, Cobos Estefania, Garcia-Bru Pere, Morwani Rahul, Santamaria Juan Francisco, Arias Luis
Department of Ophthalmology, Ocular Oncology and Vitreoretinal Service, Bellvitge University Hospital, L'Hospitalet de Llobregat, 08907 Barcelona, Spain.
Department of Brachytherapy, Catalan Institute of Oncology, Avinguda de la Gran Vía de l'Hospitalet, L'Hospitalet de Llobregat, 08908 Barcelona, Spain.
J Clin Med. 2022 Dec 1;11(23):7156. doi: 10.3390/jcm11237156.
Surgical resection is widely used to treat small tumours located in the iris and the ciliary body, due to the accessibility of these sites. By contrast, surgical removal of choroidal tumours is substantially more challenging, which is why this procedure is performed only at specialised centres. In the present article, we review the literature on surgical resection of choroidal tumours, which can be performed as endoresection (ab interno) or transscleral resection (ab externo). An important aim of this review is to describe and compare the two approaches in terms of visual outcomes, survival rates, and complications. Both approaches are indicated for the removal of large tumours (thickness > 8 mm) with small base diameters. Surgical resection of the tumour allows clinicians to obtain valuable histopathologic and cytogenetic data from the specimen and eliminates the risks associated with radiotherapy. However, both of these surgical approaches are technically challenging procedures involving the risk of severe early and late postoperative complications.
由于虹膜和睫状体部位易于手术操作,手术切除被广泛用于治疗位于这些部位的小肿瘤。相比之下,脉络膜肿瘤的手术切除则具有更大的挑战性,这就是该手术仅在专业中心进行的原因。在本文中,我们回顾了关于脉络膜肿瘤手术切除的文献,该手术可通过内切除(经眼内)或经巩膜切除(经眼外)进行。本综述的一个重要目的是从视觉效果、生存率和并发症方面描述和比较这两种方法。这两种方法均适用于切除基底直径小的大肿瘤(厚度>8mm)。肿瘤的手术切除使临床医生能够从标本中获得有价值的组织病理学和细胞遗传学数据,并消除了与放疗相关的风险。然而,这两种手术方法在技术上都是具有挑战性的操作,存在严重的早期和晚期术后并发症风险。