Department of Cardiology, Chengdu Second People's Hospital, Chengdu, China.
Department of Epidemiology and Health Statistics, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, China.
Front Public Health. 2022 Nov 24;10:865870. doi: 10.3389/fpubh.2022.865870. eCollection 2022.
The aim of our study was to assess the prevalence and geographic variation of obesity-related hypertension in China among adults aged 45 years or older.
Data were derived from the China Health and Retirement Longitudinal Study (CHARLS) conducted in 2015. Stratified sample households covered 150 counties/districts and 450 villages/urban communities from 28 provinces by using household questionnaires, clinical measurements, and blood-based bioassays. A multivariable non-conditional logistic regression model was used to analyze the risk factors correlated with obesity-related hypertension.
The prevalence of obesity-related hypertension was 22.7%, ~120 million people, among adults aged 45 years or older in China. For people in the age ranges of 45-54, 55-64, 65-74, and ≥75 years, the prevalence of obesity-related hypertension was 16.7, 24.3, 27, and 26.7%, respectively, and the prevalence of obesity-related hypertension among hypertensive participants was 66.0, 60.9, 54.2, and 47.3%, respectively. Compared with non-obesity-related hypertension, the obesity-related hypertensive patients had a higher prevalence of diabetes mellitus, dyslipidemia, and hyperuricemia (all < 0.0001). The prevalence of obesity-related hypertension showed a decreasing gradient from north to south and from east to west. Multivariate logistic regression analysis showed that female gender, living in urban areas, diabetes mellitus, dyslipidemia, and hyperuricemia were positively correlated with obesity-related hypertension.
The prevalence of obesity-related hypertension among adults aged 45 years or older was high in China. Among hypertensive participants, older age was negatively correlated with obesity-related hypertension. Obesity-related hypertensive participants are more prone to aggregation of risk factors of atherosclerotic cardiovascular disease.
本研究旨在评估中国 45 岁及以上成年人中与肥胖相关的高血压的流行情况及其地域差异。
数据来源于 2015 年开展的中国健康与养老追踪调查(CHARLS)。采用家庭问卷、临床测量和基于血液的生物检测方法,对 28 个省的 150 个县/区和 450 个村/城镇社区的分层抽样家庭进行了调查。采用多变量非条件逻辑回归模型分析与肥胖相关的高血压相关的危险因素。
在中国 45 岁及以上成年人中,与肥胖相关的高血压患病率为 22.7%,约 1.2 亿人。在 45-54、55-64、65-74 和≥75 岁年龄组中,与肥胖相关的高血压患病率分别为 16.7%、24.3%、27%和 26.7%,而高血压患者中与肥胖相关的高血压患病率分别为 66.0%、60.9%、54.2%和 47.3%。与非肥胖相关的高血压相比,肥胖相关的高血压患者更易患有糖尿病、血脂异常和高尿酸血症(均<0.0001)。与肥胖相关的高血压的患病率呈从北到南、从东到西逐渐降低的梯度。多变量逻辑回归分析表明,女性、居住在城镇、糖尿病、血脂异常和高尿酸血症与肥胖相关的高血压呈正相关。
中国 45 岁及以上成年人中与肥胖相关的高血压患病率较高。在高血压患者中,年龄较大与肥胖相关的高血压呈负相关。肥胖相关的高血压患者更易聚集动脉粥样硬化性心血管疾病的危险因素。