Tan Wanying, Qi Lingjun, Hu Xiaoyu, Tan Zhenghuai
Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Sichuan Academy of Traditional Chinese Medicine, Chengdu, China.
Front Pharmacol. 2022 Nov 24;13:921794. doi: 10.3389/fphar.2022.921794. eCollection 2022.
Alzheimer's disease (AD) is the world's leading cause of dementia and has become a huge economic burden on nations and families. However, the exact etiology of AD is still unknown, and there are no efficient medicines or methods to prevent the deterioration of cognition. Traditional Chinese medicine (TCM) has made important contributions in the battle against AD based on the characteristics of multiple targets of TCM. This study reviewed the treatment strategies and new discoveries of traditional Chinese medicine in current research, which may be beneficial to new drug researchers.
阿尔茨海默病(AD)是全球痴呆症的主要病因,已给各国和家庭带来巨大经济负担。然而,AD的确切病因仍不清楚,也没有有效的药物或方法来防止认知功能恶化。基于中药多靶点的特点,中药在对抗AD的战斗中做出了重要贡献。本研究综述了当前研究中中药的治疗策略和新发现,这可能对新药研究人员有益。