Action Contre la Faim, Paris, France.
Université de Montpellier, Montpellier, France.
PLoS One. 2022 Dec 12;17(12):e0278980. doi: 10.1371/journal.pone.0278980. eCollection 2022.
Acute malnutrition is one of the main causes of morbidity and mortality among children under 5 years worldwide, and Action Contre la Faim (ACF) aims to address its causes and consequences. To better tailor humanitarian programs, ACF conducts standardized contextual studies called Link NCAs (Nutrition Causal Analysis), to identify factors associated with severe acute malnutrition (SAM) and moderate acute malnutrition (MAM). Data from three Link NCAs performed in 2018 and 2019 in Haiti, Burkina Faso and Madagascar were used to explore the prevalence of malnutrition by different indicators and associated risk factors among children aged 6-59 months.
Cross-sectional data, collected via household surveys applying two-stage cluster sampling, were pooled to build a sample of 1,356 children. Recommended anthropometric thresholds were used to define SAM (Weight-for-Height Z-score (WHZ) <-3 or Mid-upper Arm Circumference (MUAC) <115 mm and/or presence oedema), MAM (-3≤WHZ<-2 or 115≤MUAC<125 mm) and global acute malnutrition GAM (SAM or MAM) among children. Multivariate analyses for each anthropometric indicator were performed using logistic mixed models and adjusting for potential confounders.
The prevalence of acute malnutrition was the highest in Madagascar. The risk of having GAM and MAM varied across countries, while the risk of having SAM varied across clusters. Being male, suffering from diarrhea, and having unwashed face and hands, were significantly associated with GAM by WHZ with adjusted odds ratio of 1.9 [95%Confidence interval (CI):1.1-3.2], 1.7 (95%CI: 1.0-3.1) and 1.9 (95%CI: 1.0-3.6) respectively. These factors were also associated with MAM by WHZ. None of the studied factors was significantly associated with SAM, which could be due to a small sample size.
These results obtained from a large sample contribute to the evidence of the factors associated with undernutrition in children aged 6-59 months. Further research with larger sample sizes is needed to confirm these results.
急性营养不良是全球 5 岁以下儿童发病和死亡的主要原因之一,而“行动抗饥饿”组织(ACF)旨在解决其病因和后果。为了更好地调整人道主义方案,ACF 开展了标准化的情境研究,称为 Link NCAs(营养因果分析),以确定与严重急性营养不良(SAM)和中度急性营养不良(MAM)相关的因素。使用了 2018 年和 2019 年在海地、布基纳法索和马达加斯加进行的三次 Link NCAs 的数据,以探讨不同指标下 6-59 个月儿童营养不良的流行率和相关危险因素。
通过两阶段聚类抽样进行家庭调查收集的横断面数据被汇总为一个包含 1356 名儿童的样本。使用推荐的人体测量学阈值来定义 SAM(身高体重 Z 评分(WHZ)<-3 或中上臂围(MUAC)<115mm 和/或存在水肿)、MAM(-3≤WHZ<-2 或 115≤MUAC<125mm)和全球急性营养不良 GAM(SAM 或 MAM)。使用逻辑混合模型对每个人体测量指标进行多变量分析,并调整潜在混杂因素。
急性营养不良的患病率在马达加斯加最高。各国之间 GAM 和 MAM 的风险不同,而 SAM 的风险则因聚类而异。男性、腹泻、面部和手部未清洗与 WHZ 调整后的 GAM 显著相关,优势比(OR)分别为 1.9(95%置信区间(CI):1.1-3.2)、1.7(95%CI:1.0-3.1)和 1.9(95%CI:1.0-3.6)。这些因素也与 WHZ 调整后的 MAM 相关。没有任何研究因素与 SAM 显著相关,这可能是由于样本量较小。
这些从大样本中获得的结果有助于为 6-59 个月儿童营养不良的相关因素提供证据。需要进一步开展样本量更大的研究来证实这些结果。