一种AAA型ATP酶将线粒体分裂与DNA核小体联系起来。 - Suppr

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超能文献

An AAA-ATPase links mitochondrial division with DNA nucleoids.

作者信息

Yeung Nelson, Iijima Miho, Sesaki Hiromi

机构信息

Department of Cell Biology, Johns Hopkins University School of Medicine, Baltimore, MD 21205.

出版信息

Proc Natl Acad Sci U S A. 2022 Dec 20;119(51):e2217949119. doi: 10.1073/pnas.2217949119. Epub 2022 Dec 12.

DOI:10.1073/pnas.2217949119

PMID:36508657

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9907133/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04ce/9907133/c8db801194ca/pnas.2217949119fig01.jpg

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Nature. 2021 May;593(7859):435-439. doi: 10.1038/s41586-021-03510-6. Epub 2021 May 5.

Mitochondrial division, fusion and degradation.线粒体分裂、融合和降解。

J Biochem. 2020 Mar 1;167(3):233-241. doi: 10.1093/jb/mvz106.

ATAD3A oligomerization causes neurodegeneration by coupling mitochondrial fragmentation and bioenergetics defects.ATAD3A 寡聚化通过耦联线粒体片段化和生物能缺陷导致神经退行性变。

Nat Commun. 2019 Mar 26;10(1):1371. doi: 10.1038/s41467-019-09291-x.

Mitochondrial genetic medicine.线粒体遗传医学。

Nat Genet. 2018 Dec;50(12):1642-1649. doi: 10.1038/s41588-018-0264-z. Epub 2018 Oct 29.

SnapShot: Mitochondrial Nucleoid.快照：线粒体类核。

Cell. 2018 Jan 11;172(1-2):388-388.e1. doi: 10.1016/j.cell.2017.12.039.

ATAD3 gene cluster deletions cause cerebellar dysfunction associated with altered mitochondrial DNA and cholesterol metabolism.ATAD3基因簇缺失导致与线粒体DNA和胆固醇代谢改变相关的小脑功能障碍。

Brain. 2017 Jun 1;140(6):1595-1610. doi: 10.1093/brain/awx094.

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