College of Chemistry and Molecular Engineering, Nanjing Tech University, Nanjing 211800, PR China.
College of Chemistry and Molecular Engineering, Nanjing Tech University, Nanjing 211800, PR China.
Spectrochim Acta A Mol Biomol Spectrosc. 2023 Mar 15;289:122219. doi: 10.1016/j.saa.2022.122219. Epub 2022 Dec 7.
Phosphotungstic acid covered with CeO hollow nanospheres (CeO@PTA HNSs) has been successfully prepared by a simple method, serving as highly efficient nanozymes for ascorbic acid (AA) colorimetric sensing. In virtue of the unique hollow nanostructures, oxide defects and synergic effects of CeO and PTA, the proposed CeO@PTA HNSs present remarkable intrinsic oxidase-like activity and help capture electrons from 3,3',5,5'-tetramethylbenzidine (TMB). Due to the reducibility of AA, a promising colorimetric sensing platform based on CeO@PTA HNSs has been constructed for quantitative analysis of AA. The present colorimetric detection exhibits a low limit of detection, good selectivity and stability, as well as reliability in orange juice and milk. This work provides a simple surface defect engineering to prepare high-performance oxidase mimics in the application of colorimetric biosensing.
磷钨酸包覆的氧化铈空心纳米球（CeO@PTA HNSs）已通过一种简单的方法成功制备，可用作用于检测抗坏血酸（AA）的比色传感的高效纳米酶。得益于独特的空心纳米结构、氧化铈的氧化物缺陷和与磷钨酸的协同作用，所提出的 CeO@PTA HNSs 具有显著的固有过氧化物酶样活性，并有助于从 3,3',5,5'-四甲基联苯胺（TMB）捕获电子。由于 AA 的可还原性，构建了基于 CeO@PTA HNSs 的有前景的比色传感平台，用于 AA 的定量分析。这种比色检测具有低检测限、良好的选择性和稳定性，以及在橙汁和牛奶中的可靠性。这项工作提供了一种简单的表面缺陷工程，用于在比色生物传感应用中制备高性能的过氧化物酶模拟物。
