基于一种新的抗体检测方法的腮腺炎预防措施
Mumps prophylaxis in the light of a new test for antibody.
作者信息
Mortimer P P
出版信息
Br Med J. 1978 Dec 2;2(6151):1523-4. doi: 10.1136/bmj.2.6151.1523.
A radial haemolysis test was used to investigate immunity to mumps. Antibody was found in 92 (42%) out of 220 children aged up to 5 years, 124 (78%) out of 159 children aged 6--10 years, 192 (86%) out of 222 children aged 11 years, 138 (92%) out of 150 children aged 15 years, and 280 (95%) out of 296 women attending an antenatal clinic. A group of 307 cadets aged 16--18 years were also tested and interviewed: 133 (95%) out of 140 who said that they had had mumps and 108 (87%) out of 124 who said that they had not had mumps were found to have antibody. The results suggest that tests for immunity to mumps by radial haemolysis would permit more rational use of mumps-specific immunoglobulin and attenuated mumps vaccine.
采用放射状溶血试验来研究对腮腺炎的免疫力。在220名5岁及以下儿童中，有92名（42%）检测到抗体；在159名6至10岁儿童中，有124名（78%）；在222名11岁儿童中，有192名（86%）；在150名15岁儿童中，有138名（92%）；在296名参加产前检查的妇女中，有280名（95%）。还对一组307名16至18岁的军校学员进行了检测和访谈：在140名自称患过腮腺炎的学员中，有133名（95%）检测到抗体；在124名自称未患过腮腺炎的学员中，有108名（87%）检测到抗体。结果表明，通过放射状溶血试验检测腮腺炎免疫力，将有助于更合理地使用腮腺炎特异性免疫球蛋白和减毒腮腺炎疫苗。
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