Radiology and Diagnostic Imaging Unit, Department of Clinical and Dermatological Research, San Gallicano Dermatological Institute IRCCS, 00144 Rome, Italy.
SAFU, Department of Research, Advanced Diagnostics, and Technological Innovation, IRCCS-Regina Elena National Cancer Institute, 00144 Rome, Italy.
Cells. 2022 Dec 8;11(24):3965. doi: 10.3390/cells11243965.
Artificial intelligence (AI), a field of research in which computers are applied to mimic humans, is continuously expanding and influencing many aspects of our lives. From electric cars to search motors, AI helps us manage our daily lives by simplifying functions and activities that would be more complex otherwise. Even in the medical field, and specifically in oncology, many studies in recent years have highlighted the possible helping role that AI could play in clinical and therapeutic patient management. In specific contexts, clinical decisions are supported by "intelligent" machines and the development of specific softwares that assist the specialist in the management of the oncology patient. Melanoma, a highly heterogeneous disease influenced by several genetic and environmental factors, to date is still difficult to manage clinically in its advanced stages. Therapies often fail, due to the establishment of intrinsic or secondary resistance, making clinical decisions complex. In this sense, although much work still needs to be conducted, numerous evidence shows that AI (through the processing of large available data) could positively influence the management of the patient with advanced melanoma, helping the clinician in the most favorable therapeutic choice and avoiding unnecessary treatments that are sure to fail. In this review, the most recent applications of AI in melanoma will be described, focusing especially on the possible finding of this field in the management of drug treatments.
人工智能(AI)是一个研究领域,旨在应用计算机模拟人类,它不断发展并影响着我们生活的许多方面。从电动汽车到搜索引擎,人工智能通过简化原本复杂的功能和活动,帮助我们管理日常生活。即使在医学领域,特别是肿瘤学领域,近年来的许多研究也强调了人工智能在临床和治疗患者管理方面可能发挥的有益作用。在特定情况下,智能机器和特定软件的发展支持临床决策,这些软件可以帮助专家管理肿瘤患者。黑色素瘤是一种高度异质性疾病,受多种遗传和环境因素的影响,目前在晚期仍难以临床管理。由于内在或继发耐药的出现,治疗往往会失败,使得临床决策变得复杂。在这种情况下,尽管还有很多工作要做,但大量证据表明,人工智能(通过处理大量可用数据)可以积极影响晚期黑色素瘤患者的管理,帮助临床医生做出最有利的治疗选择,并避免不必要的、注定失败的治疗。在这篇综述中,将描述人工智能在黑色素瘤中的最新应用,特别是在药物治疗管理方面的潜在发现。