炎症性肠病的遗传和表观遗传学病因：最新研究进展。
Genetic and Epigenetic Etiology of Inflammatory Bowel Disease: An Update.
机构信息
Institute of Health Sciences, Medical College of Rzeszow University, 35-959 Rzeszow, Poland.
Institute of Medicine, Medical College of Rzeszow University, 35-959 Rzeszow, Poland.
出版信息
Genes (Basel). 2022 Dec 16;13(12):2388. doi: 10.3390/genes13122388.
Abstract
Inflammatory bowel disease (IBD) is a chronic disease with periods of exacerbation and remission of the disease. The etiology of IBD is not fully understood. Many studies point to the presence of genetic, immunological, environmental, and microbiological factors and the interactions between them in the occurrence of IBD. The review looks at genetic factors in the context of both IBD predisposition and pharmacogenetics.
摘要
炎症性肠病（IBD）是一种慢性疾病，具有疾病加重和缓解的时期。IBD 的病因尚未完全阐明。许多研究指出，遗传、免疫、环境和微生物因素以及它们之间的相互作用在 IBD 的发生中起作用。本综述从 IBD 易感性和药物遗传学的角度探讨了遗传因素。
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