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肠道微生物群-脑-肠轴与痴呆:文献计量学分析。

The Microbiome-Gut-Brain Axis and Dementia: A Bibliometric Analysis.

机构信息

Unit of Psychiatry, Department of Public Health and Medicinal Administration, Institute of Translational Medicine, Faculty of Health Sciences, University of Macau, Macao SAR, China.

Centre for Cognitive and Brain Sciences, University of Macau, Macao SAR, China.

出版信息

Int J Environ Res Public Health. 2022 Dec 9;19(24):16549. doi: 10.3390/ijerph192416549.

DOI:10.3390/ijerph192416549
PMID:36554429
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9779855/
Abstract

BACKGROUND

Associations between the microbiome-gut-brain axis and dementia have attracted considerable attention in research literature. This study examined the microbiome-gut-brain axis and dementia-related research from a bibliometric perspective.

METHODS

A search for original research and review articles on the microbiome-gut-brain axis and dementia was conducted in the Web of Science Core Collection (WOSCC) database. The R package "bibliometrix" was used to collect information on countries, institutions, authors, journals, and keywords. VOSviewer software was used to visualize the co-occurrence network of keywords.

RESULTS

Overall, 494 articles met the study inclusion criteria, with an average of 29.64 citations per article. Corresponding authors of published articles were mainly from China, the United States and Italy. Zhejiang University in China and Kyung Hee University in Korea were the most active institutions, while the and published the most articles in this field. Expected main search terms, "Parkinson disease" and "chain fatty-acids" were high-frequency keywords that indicate current and future research directions in this field.

CONCLUSIONS

This bibliometric study helped researchers to identify the key topics and trends in the microbiome-gut-brain axis and dementia-related research. High-frequency keywords identified in this study reflect current trends and possible future directions in this field related to methodologies, mechanisms and populations of interest.

摘要

背景

微生物群-肠-脑轴与痴呆之间的关联在研究文献中引起了相当大的关注。本研究从文献计量学的角度考察了微生物群-肠-脑轴与痴呆相关的研究。

方法

在 Web of Science 核心合集(WOSCC)数据库中对微生物群-肠-脑轴与痴呆相关的原始研究和综述文章进行了检索。使用 R 包“bibliometrix”收集有关国家、机构、作者、期刊和关键词的信息。VOSviewer 软件用于可视化关键词的共现网络。

结果

总体而言,有 494 篇文章符合研究纳入标准,平均每篇文章引用 29.64 次。发表文章的通讯作者主要来自中国、美国和意大利。中国的浙江大学和韩国的庆熙大学是最活跃的机构,而 和 在该领域发表的文章最多。预期的主要检索词“帕金森病”和“链脂肪酸”是高频关键词,表明了该领域当前和未来的研究方向。

结论

这项文献计量研究帮助研究人员确定了微生物群-肠-脑轴与痴呆相关研究的关键主题和趋势。本研究中确定的高频关键词反映了该领域与方法学、机制和感兴趣人群相关的当前趋势和可能的未来方向。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d974/9779855/1a4349233180/ijerph-19-16549-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d974/9779855/d01e2ab26388/ijerph-19-16549-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d974/9779855/d5456b8aac4c/ijerph-19-16549-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d974/9779855/2e3cddf7b621/ijerph-19-16549-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d974/9779855/42b591b1eb8a/ijerph-19-16549-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d974/9779855/a8126dae75c4/ijerph-19-16549-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d974/9779855/1a4349233180/ijerph-19-16549-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d974/9779855/d01e2ab26388/ijerph-19-16549-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d974/9779855/d5456b8aac4c/ijerph-19-16549-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d974/9779855/2e3cddf7b621/ijerph-19-16549-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d974/9779855/42b591b1eb8a/ijerph-19-16549-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d974/9779855/a8126dae75c4/ijerph-19-16549-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d974/9779855/1a4349233180/ijerph-19-16549-g006.jpg

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