Shin Seyoung, Lee Hwang-Jae, Chang Won Hyuk, Ko Sung Hwa, Shin Yong-Il, Kim Yun-Hee
Department of Physical and Rehabilitation Medicine, Center for Prevention and Rehabilitation, Heart Vascular Stroke Institute, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 06351, Republic of Korea.
Robot Business Team, Samsung Electronics, Suwon 16677, Republic of Korea.
J Clin Med. 2022 Dec 10;11(24):7343. doi: 10.3390/jcm11247343.
This study was a randomized controlled trial to examine the effects of the RAPAEL Smart Glove digital training system on upper extremity function and cortical hemodynamic changes in subacute stroke patients. Of 48 patients, 20 experimental and 16 controls completed the study. In addition to conventional occupational therapy (OT), the experimental group received game-based digital hand motor training with the RAPAEL Smart Glove digital system, while the control group received extra OT for 30 min. The Fugl-Meyer assessment (UFMA) and Jebsen-Tayler hand function test (JTT) were assessed before (T0), immediately after (T1), and four weeks after intervention (T2). Cortical hemodynamics (oxyhemoglobin [OxyHb] concentration) were measured by functional near-infrared spectroscopy. The experimental group had significantly better improvements in UFMA (T1-T0 mean [SD]; Experimental 13.50 [7.49]; Control 8.00 [4.44]; = 0.014) and JTT (Experimental 21.10 [20.84]; Control 5.63 [5.06]; = 0.012). The OxyHb concentration change over the ipsilesional primary sensorimotor cortex during the affected wrist movement was greater in the experimental group (T1, Experimental 0.7943 × 10 μmol/L; Control -0.3269 × 10 μmol/L; = 0.025). This study demonstrated a beneficial effect of game-based virtual reality training with the RAPAEL Smart Glove digital system with conventional OT on upper extremity motor function in subacute stroke patients.
本研究是一项随机对照试验，旨在探讨RAPAEL智能手套数字训练系统对亚急性卒中患者上肢功能及皮质血流动力学变化的影响。48例患者中，20例实验组和16例对照组完成了研究。除常规职业治疗（OT）外，实验组使用RAPAEL智能手套数字系统接受基于游戏的数字手部运动训练，而对照组接受额外30分钟的OT。在干预前（T0）、干预后即刻（T1）和干预后四周（T2）进行Fugl-Meyer评估（UFMA）和Jebsen-Taylor手部功能测试（JTT）。通过功能近红外光谱测量皮质血流动力学（氧合血红蛋白[OxyHb]浓度）。实验组在UFMA（T1-T0均值[标准差]；实验组13.50[7.49]；对照组8.00[4.44]；P=0.014）和JTT（实验组21.10[20.84]；对照组5.63[5.06]；P=0.012）方面有显著更好的改善。实验组在患侧手腕运动期间同侧初级感觉运动皮层的OxyHb浓度变化更大（T1，实验组0.7943×10μmol/L；对照组-0.3269×10μmol/L；P=0.025）。本研究证明，使用RAPAEL智能手套数字系统进行基于游戏的虚拟现实训练结合常规OT对亚急性卒中患者的上肢运动功能有有益影响。
