Jalalvandi Maziar, Riyahi Alam Nader, Sharini Hamid, Hashemi Hasan, Nadimi Mohadeseh
MSc, Department of Medical Physics and Biomedical Engineering, School of Medicine, Tehran University of Medical Sciences (TUMS), Tehran, Iran.
PhD, Department of Medical Physics and Biomedical Engineering, School of Medicine, Tehran University of Medical Sciences (TUMS), Tehran, Iran.
J Biomed Phys Eng. 2021 Oct 1;11(5):583-594. doi: 10.31661/jbpe.v0i0.1051. eCollection 2021 Oct.
fNIRS is a useful tool designed to record the changes in the density of blood's oxygenated hemoglobin (oxyHb) and deoxygenated hemoglobin (deoxyHb) molecules during brain activity. This method has made it possible to evaluate the hemodynamic changes of the brain during neuronal activity in a completely non-aggressive manner.
The present study has been designed to investigate and evaluate the brain cortex activities during imagining of the execution of wrist motor tasks by comparing fMRI and fNIRS imaging methods.
This novel observational Optical Imaging study aims to investigate the brain motor cortex activity during imagining of the right wrist motor tasks in vertical and horizontal directions. To perform the study, ten healthy young right-handed volunteers were asked to think about right-hand movements in different directions according to the designed movement patterns. The required data were collected in two wavelengths, including 845 and 763 nanometers using a 48 channeled fNIRS machine.
Analysis of the obtained data showed the brain activity patterns during imagining of the execution of a movement are formed in various points of the motor cortex in terms of location. Moreover, depending on the direction of the movement, activity plans have distinguishable patterns. The results showed contralateral M1 was mainly activated during imagining of the motor cortex (p<0.05).
The results of our study showed that in brain imaging, it is possible to distinguish between patterns of activities during wrist motion in different directions using the recorded signals obtained through near-infrared Spectroscopy. The findings of this study can be useful in further studies related to movement control and BCI.
功能近红外光谱技术（fNIRS）是一种用于记录大脑活动期间血液中氧合血红蛋白（oxyHb）和脱氧血红蛋白（deoxyHb）分子密度变化的有用工具。这种方法使得以完全无创的方式评估神经元活动期间大脑的血流动力学变化成为可能。
本研究旨在通过比较功能磁共振成像（fMRI）和功能近红外光谱成像方法，研究和评估在想象执行腕部运动任务期间大脑皮层的活动。
这项新颖的观察性光学成像研究旨在研究在想象垂直和水平方向的右手腕运动任务期间大脑运动皮层的活动。为了进行这项研究，10名健康的年轻右利手志愿者被要求根据设计的运动模式想象右手在不同方向的运动。使用48通道的fNIRS机器在845和763纳米两个波长下收集所需数据。
对获得的数据进行分析表明，在想象执行运动期间的大脑活动模式在运动皮层的不同位置形成。此外，根据运动方向，活动模式具有可区分的特征。结果表明，在想象运动皮层期间，对侧M1主要被激活（p<0.05）。
我们的研究结果表明，在脑成像中，使用通过近红外光谱获得的记录信号可以区分不同方向腕部运动期间的活动模式。本研究结果可用于与运动控制和脑机接口相关的进一步研究。
