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鼻窦和鼻腔疾病的当前及新兴治疗选择:合适疗法的光明未来。

Current and Emerging Treatment Options in Sinus and Nasal Diseases: A Promising Future in the Appropriate Therapies.

作者信息

Lin Lin, Cheng Lei

机构信息

Department of Otorhinolaryngology-Head and Neck Surgery, Huashan Hospital of Fudan University, Shanghai 200040, China.

Department of Otorhinolaryngology & Clinical Allergy Center, The First Affiliated Hospital, Nanjing Medical University, Nanjing 210029, China.

出版信息

J Clin Med. 2022 Dec 14;11(24):7398. doi: 10.3390/jcm11247398.

DOI:10.3390/jcm11247398
PMID:36556014
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9788022/
Abstract

Chronic rhinosinusitis (CRS) is an inflammatory condition of the nose and paranasal sinuses defined by clinical symptoms, including two or more symptoms, one of which should be either nasal blockage or nasal discharge with or without facial pain/pressure or reduction in/loss of sense of smell [...].

摘要

慢性鼻-鼻窦炎(CRS)是一种发生于鼻腔和鼻窦的炎症性疾病,由临床症状定义,包括两种或更多症状,其中之一应为鼻塞或流涕,伴有或不伴有面部疼痛/压迫感或嗅觉减退/丧失[...]。

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J Clin Med. 2022 Dec 14;11(24):7398. doi: 10.3390/jcm11247398.
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本文引用的文献

1
Yardstick for the medical management of chronic rhinosinusitis.慢性鼻-鼻窦炎的医学管理标准。
Ann Allergy Asthma Immunol. 2022 Feb;128(2):118-128. doi: 10.1016/j.anai.2021.10.014. Epub 2021 Oct 20.
2
Efficacy and safety of benralizumab in chronic rhinosinusitis with nasal polyps: A randomized, placebo-controlled trial.贝那鲁肽治疗伴有鼻息肉的慢性鼻-鼻窦炎的疗效和安全性:一项随机、安慰剂对照试验。
J Allergy Clin Immunol. 2022 Apr;149(4):1309-1317.e12. doi: 10.1016/j.jaci.2021.08.030. Epub 2021 Sep 29.
3
Mepolizumab for chronic rhinosinusitis with nasal polyps (SYNAPSE): a randomised, double-blind, placebo-controlled, phase 3 trial.美泊利单抗治疗伴有鼻息肉的慢性鼻-鼻窦炎(SYNAPSE):一项随机、双盲、安慰剂对照、3 期临床试验。
Lancet Respir Med. 2021 Oct;9(10):1141-1153. doi: 10.1016/S2213-2600(21)00097-7. Epub 2021 Apr 16.
4
International consensus statement on allergy and rhinology: rhinosinusitis 2021.《2021年变应性鼻炎和鼻科学国际共识声明:鼻窦炎》
Int Forum Allergy Rhinol. 2021 Mar;11(3):213-739. doi: 10.1002/alr.22741.
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Adult-onset eosinophilic airway diseases.成人起病的嗜酸性气道疾病。
Allergy. 2020 Dec;75(12):3087-3099. doi: 10.1111/all.14620. Epub 2020 Oct 23.
6
Efficacy and safety of omalizumab in nasal polyposis: 2 randomized phase 3 trials.奥马珠单抗治疗鼻息肉的疗效和安全性:两项随机 3 期临床试验。
J Allergy Clin Immunol. 2020 Sep;146(3):595-605. doi: 10.1016/j.jaci.2020.05.032. Epub 2020 Jun 7.
7
The Role of Macrolides and Doxycycline in Chronic Rhinosinusitis.大环内酯类药物和多西环素在慢性鼻-鼻窦炎中的作用。
Immunol Allergy Clin North Am. 2020 May;40(2):303-315. doi: 10.1016/j.iac.2019.12.005. Epub 2020 Jan 18.
8
European Position Paper on Rhinosinusitis and Nasal Polyps 2020.欧洲鼻窦炎和鼻息肉 2020 年立场文件。
Rhinology. 2020 Feb 20;58(Suppl S29):1-464. doi: 10.4193/Rhin20.600.
9
A comparison of international clinical practice guidelines on adult chronic rhinosinusitis shows considerable variability of recommendations for diagnosis and treatment.一项针对成人慢性鼻-鼻窦炎国际临床实践指南的比较研究显示,在诊断和治疗建议方面存在相当大的差异。
Eur Arch Otorhinolaryngol. 2020 Mar;277(3):659-668. doi: 10.1007/s00405-019-05752-7. Epub 2019 Dec 16.
10
Radiologic sinus inflammation and symptoms of chronic rhinosinusitis in a population-based sample.基于人群样本的放射学鼻窦炎症与慢性鼻-鼻窦炎症状。
Allergy. 2020 Apr;75(4):911-920. doi: 10.1111/all.14106. Epub 2019 Dec 2.