Key Laboratory of Chinese Medicine Resources Conservation, State Administration of Traditional Chinese Medicine of China, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, 100193, China.
Jiangxi University of Chinese Medicine, Nanchang, 330000, Jiangxi, China.
Mol Biotechnol. 2023 Aug;65(8):1207-1227. doi: 10.1007/s12033-022-00641-7. Epub 2022 Dec 23.
RNA editing is a post-transcriptional process that introduces changes in RNA sequences encoded by nuclear, mitochondrial, or plastid genomes. To understand the research progress of plant RNA editing, we comprehensively analyze the articles on plant RNA editing from 2001 to 2022 through bibliometric methods. Nucleic Acids Research, Plant Journal and Plant cell are the journals that deserve attention with their high production, total local citation scores (TLCS), and h-indexes. The USA, China, and Germany are the top three countries with highly productive publications. Ulm University, Cornell University, and Chinese Acad Sci are excellent cooperative institutions with a high level of influence in the field, and KNOOP V and TAKENAKA M are good partnership. Plant RNA editing researches concentrate on the subject categories of Biochemistry & Molecular Biology, Plant Sciences, Genetics & Heredity, etc. Plant mitochondria, genome editing and messenger-RNA may be the research hotspots in the future. The main plant RNA editing research tools are JACUSA, SPRINT, and REDO, and the main databases are REDIdb, PED, and dbRES. At present, the research streams are (1) RNA editing sites; (2) Pentapeptide repeat protein (PPR) involved in RNA editing; (3) RNA editing factors. Overall, this article summarizes the research overview of plant RNA editing until 2022 and provides theoretical implications for its possible future directions.
RNA 编辑是一种在核基因组、线粒体基因组或质体基因组编码的 RNA 序列中引入变化的转录后过程。为了了解植物 RNA 编辑的研究进展，我们通过文献计量学方法对 2001 年至 2022 年期间关于植物 RNA 编辑的文章进行了全面分析。《核酸研究》《植物杂志》和《植物细胞》是值得关注的期刊，它们的发文量高、总本地引文得分（TLCS）和 h 指数高。美国、中国和德国是发表高产论文的前三个国家。乌尔姆大学、康奈尔大学和中国科学院是该领域具有高影响力的优秀合作机构，KNOOP V 和 TAKENAKA M 是很好的合作伙伴。植物 RNA 编辑研究集中在生物化学与分子生物学、植物科学、遗传学与遗传等学科类别。植物线粒体、基因组编辑和信使 RNA 可能是未来的研究热点。主要的植物 RNA 编辑研究工具是 JACUSA、SPRINT 和 REDO，主要的数据库是 REDIdb、PED 和 dbRES。目前，研究方向有（1）RNA 编辑位点；（2）参与 RNA 编辑的五肽重复蛋白（PPR）；（3）RNA 编辑因子。总之，本文总结了截至 2022 年植物 RNA 编辑的研究概况，并为其未来可能的方向提供了理论启示。
