In 2020, the COVID-19 pandemic has spread worldwide. To alleviate this spread, various blockade policies have been implemented in many areas. This has led to a sluggish demand in the world's major economies, sharp drop in the trade index, and negative growth in energy consumption. To formulate a better epidemic prevention policy for urban energy consumption of commercial tourism cities, this study summarizes the major statistics of energy supply and demand before and during the epidemic period based on actual data. The characteristics of energy consumption in different sectors, including hotels, transportation, tourism culture, and public utilities, are then analyzed in detail. Finally, the energy consumption features of commercial tourism cities represented by Macao are compared to those of other typical countries (e.g., Italy, United States, Japan, and Brazil). These analyses demonstrate the impact of COVID-19 on the energy consumption in commercial tourism cities, which provides insights for the government or energy providers to formulate policies to adapt to this pandemic.