Brennan M D, Klee G G, Preissner C M, Hay I D
Division of Endocrinology/Metabolism, Mayo Clinic, Rochester, MN 55905.
Mayo Clin Proc. 1987 Oct;62(10):894-8. doi: 10.1016/s0025-6196(12)65044-7.
We report two cases of euthyroid patients with inappropriately elevated serum levels of thyrotropin (TSH) in whom investigation led to the detection of heterophilic antibodies. In addition, we compare the performance of two TSH immunometric assay systems in this setting. Even when monoclonal assay systems are used, TSH results must be critically interpreted when they are at variance with clinical and other biochemical findings.
我们报告了两例甲状腺功能正常但血清促甲状腺激素(TSH)水平异常升高的患者,对其进行检查后发现了嗜异性抗体。此外,我们比较了在此情况下两种TSH免疫测定系统的性能。即使使用单克隆测定系统,当TSH结果与临床及其他生化检查结果不一致时,也必须审慎解读。